Study On The Relationship Between Arterial Stiffness Index And The Severity Degree Of Coronary Atherosclerosis

Objective: To investigate the relationship between arterial stiffnessindex (ASI) and the severity degree of coronary atherosclerosis.Methods: A total of 396 patients underwent coronary angiograph and themeasurement of ASI using CardioVision MS-2000 arterial stiffness detectorand then they were divided into three groups: groupⅠ(ASI 0-70, 186patients); groupⅡ(ASI 71-140, 108 patients); and groupⅢ(ASI＞140, 102patients). The severity degree of coronary heart disease was evaluated by thenumbers of involved coronary arteries.Results: There were significant differences in age, history of highblood pressure, diabetes history, systolic blood pressure, and the severitydegree of coronary heart disease among three groups. The mean number ofinvolved coronary arteries was highest in groupⅢfollowely by groupⅡandgroupⅠ(P＜0.05). There was a positive correlation between age, systolicblood pressure, high pressure history, diabetes history, lipoprotein (a), uricacid, ASI and the number of involved coronary arteries showed by singlefactor correlation analysis methods. However, there was a negativecorrelation between high-density lipoprotein cholesterols(HDL-C) and thenumber of involved coronary arteries (P＜0.05). ASI, HDL-C and lipoprotein(a) were independent risk factors of coronary heart disease showed by multiple factor logistic regression analysis method.Conclusion: ASI may be a good index reflecting arterial elasticity andcan provide meaningful information of the severity degree of involvedcoronary arteries.