Studies On Quality Standard Of Yiqifuzheng Injection Intermediate

The topic build up system Quality Criterion of Yiqifuzheng injection intermediate. The topic established Quality Criterion according to Panax ginseng and Salvia miltiorrhiza of《Chinese medical dictionary》2005, simultaneous add total Ginsenosides assaying and total water solubility compound assaying. Total Ginsenosides can not less than 1.0% and cctotal water solubility compound can not less than 3.0%. According to《the technical demand of new drug study about traditiona Chinese medicine》and《Chinese medical dictionary》2005, ginseng intermediate Quality Criterion and miltiorrhiza intermediate Quality Criterion were established. The ginseng intermediate is the palm tree yellow powder, moisture less than 5.0% and total Ginsenosides can not less than 73%. The miltiorrhiza intermediate is the palm tree red powder, moisture less than 10% and total water solubility compound can not less than 85.0%. The check of lamellar identification all need to meet《Chinese medical dictionary》request.The topic according to《the technical demand of the fingerprint about injection of traditional Chinese medicine》,adopted high efficiency liquid chrorhatography to draw up the fingerprint of ginseng and ginseng intermediate ,and the fingerprint of miltiorrhiza and miltiorrhiza intermediate. By analyzing the ginseng and ginseng intermediate fingerprint of 10 samples , there were 19 and 10 common peaks referring to the Ginsenosides Rb₁ . The miltiorrhiza and miltiorrhiza intermediate have 15 common peaks referring to the salvianolic acid B. The technology research all match the fingerprint request and the similarity all were more than 0.9.