Study On Effects Of The Sand Dust Storm To Population Health And Toxicology Of PM_2.5

Objective: 1.To comprehend polluted level of PM_2.5 through analysis variation characteristics of PM_2.5 concentration during the Sand Dust Storm. 2.To study the acute effects of PM_2.5 on rats by Sand Dust Storm. 3. To study influence of Sand Dust Storm to population health. Methods:1.Collect fine paniculate matter (PM_2.5) day by day during the Sand Dust Storm in Minqin county.2.40 male Wistar rats were randomly divided into four groups depending different exposure concentration of PM_2.5, exposed by intra-tracheal instillation and control group treated with physiological saline. Rats were killed 24h after treatment, the levels of ACP, AKP, LDH, SDH, ALB and TP in blood serum and BALF were examined; the levels of SOD, GSHPx and MDA in lung, Liver, Spleen and Kidney were examined. 3.(1)Clinic, emergency, hospitaiization and death case data were statisticed, day by day in six hospital, in Wuwei city, during the Sand Dust Storm, and relation with PM₁₀,SO₂,NO₂ concentration were analysed. (2) 2 primary schools and 2 community in Wu wei City were investigated by the questionnaires during the Sand Dust Storm, investigated results were treated with EPIDATA, the results were statisticed with SPSS 10.0. Results:1.The mean of PM2.5 concentration exceed American standard published in 1997, each month mean of PM2.5 is different, each month occurrence rate of the Sand Dust Storm is different, the mean of PM2.5 concentration is different between period of Sand Dust Storm and other days, the concentration of PM2.5 is the highest in forth day after Sand Dust Storm.2. Significantly increase of ACP, AKP, LDH , ALB , TP and decrease of SDH were caused between PM2.5 exposure group and control group, in blood serum and BALF. Compared with control group of physiological saline, doses of lungs, livers, Kidneys have significant difference. All antioxidases in Spleens have not significant difference among test, blank and control group of physiological saline. 3.(l)The day Sand Dust Storm occurrence and 1～2 days after this day, clinic amount of respiratory illness increased .Respiratory illness have positive relation with concentration of PM₁₀, have no relation with concentration of SO₂, NO₂. In emergency case ,accidental injury and youth are important; In hospitalization cases, respiratory disease, digestive disease, circulatory disease, detriment and intoxication are important; older and young are relatively increasing; In death case, the case fatality of circulatory disease is the largest, death case and case fatality of respiratory system are lowly. (2)The highest incidence rates of the related respiratory diseases and symptoms were found at the day when the Sand Dust Storm broke out, and lower incidence rates were found after the breaking out day in population. Conclusion: PM_2.5 of Sand Dust Storm can evoke acute toxicity damage, make danger for population, we should prevention and cure Sand Dust Storm are imminent.