The Effect Of Control Of Calcium And Phosphate Abnormality On Coronary Artery Calcification Of Peritoneal Dialysis Patients

Objective: To evaluate the effect of low-calcium peritoneal dialysate and phosphate binder on calcium and phosphate abnormality and coronary artery calcification of end-stage renal disease patients.Method: 60 peritoneal dialysis patients were divided into therapy group and control group randomly. Therapy group was prescribed low-calcium peritoneal dialysate and phosphate binder, control group was prescribed normal-calcium peritoneal dialysate. The level of serum calcium and phosphate and coronary artery calcification score were measured before and after treatment.Results: Age dialysis time phosphate the product of calcium and phosphate C reactive protein parathyroid hormone were higher in patients with CAC (39 person, 65%) than patients without CAC (21 person, 35%). Low-calcium peritoneal dialysate and phosphate binder can reduce the level of phosphate (2. 47 ±0. 52 vs 1. 91 ± 0. 65) and the product of calcium and phosphate (5.18 ± 1.08 vs 4.11 ±1.45), but have not effect on CAC. Conclusion: Low-calcium peritoneal dialysate and phosphate binder can correct calcium and phosphate abnormality but have not effect on the development of coronary artery calcification...