QTVI Study Of Ischemia-related Regional Myocardial Dysfunction In Systolic

Objective: To evaluate the Ischemia-related Regional Myocardial Asynchrony in systolic using quantitative tissue velocity imaging. Methods: 48 age-matched patients suspected CAD underwent 2-dimensional echocardiography examination before coronary angiography(CAG), LVEF was measured using Simposon's method and peak systolic velocity (Sm) and the period from electrocardiographyic R wave to peak systolic velocity(Ts) on 12 nonapical segments were acquired through 3 apical views using quantitative tissue velocity imaging. All patients were divided into 3 groups by CAG :normal group(non coronary artery disease) , CAD group 1(<75% diameter stenosis), CAD group 2(≥75% diameter stenosis) .To calculate the standard deviation of Ts on 12 segments of each patient.Result:1.Ts of basal&mid-AS , mid-PW ,mid-PS and basal&mid-LW in CAD group had delay compared with no CAD group(p<0.05), especially of basal&mid-lateral(p<0.001). Sm of CAD Groups showed significantly lower than normal group except in mid-PS and mid-LW. 2, Ts of basel and middle segments in same wall had no significant differences no matter in which group (p>0.05) There are significant differences of Ts in basal&mid-LW between coronary artery stenosis <75% group and coronary artery stenosis ≥75% group(p<0.05) . But there are no significant differences of Sm between these 2 groups (p>0.05) . 3, The change of Ts and Sm in LW may be the indicator...