Study On The Relationship Between Inflammatory Markersand ACS Sydrome Differentiation Typeof TCM, Short-time Prognosis

We assessed the levels of serum C-reaclive protein(CRP) and transforming growth factor-β1(TGF-β1) in patients with acute coronary syndtome (ACS),(1) To investigate the relationship between the levels of CRP,TGF-β1 and sydrome differentiation of ACS;(2) And to investigate the relationship between these levels and the short-time prognosis of these patients.(3) Also to discuss the possihie mechanisms by which they participate in CAD.[Methods] CRP and TGF- β 1 levels in serum were assayed by ELISA from 100 patients with ACS who all were diognosed through CAG. These patients included 79 paitients with UAP,21 ones with AMI. All patients' clinical information, including aymptoms and aigns, was collected through the four examinatons of TCM. 100 cases with ACS were classified as deficincy types,such as Qi-deficincy, Yin-deficincy, Yang-deficincy,and the excess types, such as blood stasis, phlegm-turbid, cold condensation and Qi stagnant syndrome by differentiating syndrome and type. The levels of CRPa and TGF-β1a from all patients assayed on the day of onset, and the levels of CRP and TGF- β1 from 61 followed-up patients also assayed 24 hours (CRP b, TGF- β1b)and 72 hours(CRPc, TGF- β1c) after PCI. At the same time, CK-MB, EF were also measured and some clinic data were asked on the day of being hospitalized. Those 61 patients with ACS were observed during hospital and within three months after leaving hosoptal. In hospital,those ACS patients who suffered from major heart events were assigned to group A,and the other patients who had no such events were assigned to group B. Those patients who suffered from critical cardiovascular events after leaving hospital were in group C,and those who had no such events were in group D. All data were processed by ststistics. [Results] (1) The levels of CRPa were no difference between deficincy syndrome group and excess syndrome group(15.89±21.61 vs 17.43±19.02, P>0.05).The levels of CRPa from heart-Qi deficincy syndrome group, heart-Yin deficincy syndrome group, heart-Yang deficincy syndrome group, blood stagnating the heart collaterals syndrome group, the turbid phlegm obstructing the heart sundrome group and...