Investigation Of Expression Of The ConA Related Polysaccharide With High Mannose, The RCA Related Polysaccharide With Terminal Galbetal-4GlcNAc, The SNA Related Polysaccharide With Neu5Aca2-6Gal In Serum Of Normal, Benign Disease And Malignant Tumors Pati

Background It is well known that there is a series of carbohydrate molecules in cellular membrane and human serum. Some carbohydrate molecules with special oligosaccharide have been found to be as the maker for analysis of cell function and tumor diagnosis. And the oligosaccharide plays an important role in cell recognizaton, cell identification course and cell transformation in human body. The level of the oligosaccharide is relatively stable under normal condition. The quantity and quality of the oligosaccharide may be happening to change accordingly when malignant change occurs. And the change will be reflected though combinative ability with lectin. Lectins are nonimmune glycoproteins which can identify the specific oligosaccharide. The combinative ability is similar to Teation of antigen and antibody. Lectins are divided seven species accord to their sugar combination peculiarity: (1) D-mannose or D-glucose group; (2) galactose group; (3) N-acetylgalactosamine group; (4) N-acetylglucosamine group; (5) L-Fucose group; (6) N-acetylneuraminic...