Study On The Clinical Drug Resistance In Childhood Tuberculosis And The Drug Resistance Gene

PART I. Clinical Drug Susceptibility Test Of Mycobacterium Tuberculosis And Clinical Research On Children With TuberculosisOBJECTIVE: At present, the situation of the prevention and cure of tuberculosis (TB) is becoming very complicated and difficult in our country; furthermore, the incidence of childhood TB trends to increase in recent years. The main aims of this study should be eagerly to investigate the current status of drug resistance tuberculosis (DR-TB) in childhood TB and to study the clinical characteristics of TB in children in local region, and that could be able to supply theoretic bases for anti-TB.METHODS: In this study, the specimens (of body fluid, puncture fluid of tissue, etc.) for Mycobacterium tuberculosis (MT) culture were collected from the children who were hospitalized and clinically diagnosed as TB during 2002~2005. 1class of Anti-TB drug (including INH, RIF, STM, EMB and PAS.) susceptibility tests of the MT isolates, which were...