The Systematic Study Of Aconitum L. Chinese Medicine Material Foundation In Decoction Process

Objective: Aconitum L. Chinese medicine mains come from Ranunculaceae plant Acontitum Carmichaeli Debx. and Aconitum Kusnezoffi Reichb. earthnut and side root process production. It usage history more than 2000 years in our conuntry. But Aconitum L. Chinese medicine have violent toxicity , often appear to toxicosis phenomenon in clinical application. Investigate its reason, I think thatprimarily reason is lack to scientific process technics and medicine materials standards. This lesson's according to research system Aconitum L. water decoction process each kind of ingredient contents and time correlational dependence objective to criterion Aconitum L. Chinese medicine process technics and clinical application provides a reference ; In addition, its first step toward "Systematic Study of Aconitum L. Chinese Medicine Material Foundation and Application Development"Methods: With Aconitum L. Chinese Medicine is not meantime the water that order frying liquid for research object, use anthrone—H₂SO₄ colorimetric method, TLC—S, HPLC determination the amylose, aconitine, hypaconitine, mesaconitine, benzoic acid and other contents.Results: The contents of amylose and benzoic acid along with decoction time increment but increment; The contents of aconitine, hypaconitine and mesaconitine along with different of medicine materials, decoction time, match material components and quantity shows irregular variety.Conclusion: This research is part of "Aconitum L. Chinese Medicine Safety Evaluate" objective to criterion Aconitum L. Chinese medicine process technics and clinical application provides a reference standard for the quality control.