Quantitative Analysis Of Circulating Non-Host Fetal DNA Levels In Maternal Serum In Pre-Eclampsia Pregnancies

OBJECTIVETo explore the diagnostic value and the pathogeny of pre-eclampsia with the determination of maternal serum fetal DNA. To compare the concentration of circulating non-host fetal DNA in maternal serum in pre-eclampsia pregnancies with it in normal pregnancies, will help to study the pathogeny of pre-eclampsia, and to compare the concentration in light pre-eclampsia with it in severe pre-eclampsia, might help to observe the development of the pre-eclampsia patients ' conditions and help to prognosis the eclampsia. METHODThere were 607 pregnant women who came for prenatal check-up and 56 of them were with pre-eclampsia. And 30 of the 56 pre-eclampsia women pregnant with male fetuses by B-ultrasound (witnessed after birth) were selected as the pre-eclampsia group. According to the diagnostic code of the hypertension disorder complicat- ing pregnancy (PIH) on the textbook (( obstetrics and gynecology)) (the sixth edition), these 30 cases were devided into light pre-eclampsia(14 cases), severe pre-eclampsia(17 cases) and combining the HELLP syndrome(10 cases). In addintion, 30 normal women pregnant with male fetuses by B-ultrasound ( witnessed after...