The Effects Of Ischemia-reperfusion-like Condition On Cell Activity, Intracellular Ca～(2+) And Proliferation Of Neural Stem Cells Obtained From Mice Corpus Striatum

Neural stem cells (NSCs) are defined as undifferentiated cells that are able to self-renew as well as generate three major types of cells that constitute the central nervous system: neurons, astrocytes and oligodendrocytes. NSCs can be found in many part of embryonic central nervous system such as olfactory bulb, sub ventricular zone, hippocampus, spinal cord, cerebellum and cerebral cortex. Sub ventricular zone and sub granular zone are two major places which are rich of NSCs in adult mammalian central nervous system.The discovery and successful culture of NSCs has brought the hope for the treatment of central nervous system disorders. Since the discovery, the laboratory and the clinical research on NSCs are like a raging fire. The isolation and culture of NSCs in vitro is the foundation of studies on its biological characteristics, establishment of cell lines and cell transplantation. In this study, NSCs of mice corpus striatum was isolated,...