The Clinical Characteristics And Prognostic Factors Of 118 Breast Cancer Patients With Small Tumor Size And Multi-axillary Lymph Node Metastasis

ObjectiveTo analyse the clinical characteristics and potential prognostic factors of the breast cancer patients with small tumor size and multi-axillary lymph node metastasisMethods118 breast cancer patients with small tumor size and multi-axillary lymph node metastasis (T≤2cm and N≥4) from 1993 to 2003 in our hospital were retrospectively analysed by SPSS13.0 software.ResultsThe 5-year overall survival rate was 75% for all the patients. After the single-variant's Kaplan-Merier analysis, we found that the stage, adjuvant chemotherapy and adjuvant endocrine therapy significantly influence the outcome of the patients. For stage IIIA and IIIC patients, the 5-year OS was 89.5% and 59.8%, respectively (P=0.009). For patients with and without the adjuvant chemotherapy, the 5-year OS was 82.1% and 53.3%, respectively (P=0.001). For patients with and without adjuvant endocrine therapy, the 5-year OS was 89.2% and 61.9% (P=0.001). But there was no significant difference between the patients with and without the adjuvant radiotherapy, the 5-year OS was 83.3% and 72.4% (P=0.078).After the multi-variants' cox regression analysis, we found the stage, adjuvant chemotherapy and adjuvant endocrine therapy were the independent prognostic factors.