A Study About The Plasma Adiponectin Levels And Macroangiopathy In Patients With Type 2 Diabetes Mellitus

Background and Purpose: Macroangiopathy is an important and frequent complication suffered by patients with type 2 diabetes mellitus, and is the main cause of death for type 2 diabetic patients. The early detection of macrovasclar complications in the type 2 diabetes mellitus is very important. Now the methods that are usually used in clinical to detect early macroangiopathy include vascular ultrasound measuring the carotid intima-media thickness (CIMT, reflecting the structural changes of the arteries), Pulse wave velocity (a-PWV, reflecting the functional changes of the arteries) and Pulse wave analysis and so on. Increasing attention has been paid to adiponectin for its direct vascular effects (including the structure and function of the blood vessels). In this study we detect the functional changes of arteries by automatic pulse wave measurement system, use the carotid intima-media thickness as an index measuring the degree of arteriosclerosis, and measure the plasma adiponectin levels of all subjects , in order to discuss the correlation between plasma adiponectin levels and macroangiopathy in type 2 diabetic patients.Methods: According to the 1997 ADA criteria for the...