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The Expression Of Kallikrein14 Protein In Cervical Cancer Applicant For Master Degree

Posted on:2007-09-21Degree:MasterType:Thesis
Country:ChinaCandidate:Q M YanFull Text:PDF
GTID:2144360185471241Subject:Gynecologic Oncology
Abstract/Summary:PDF Full Text Request
Cervical cancer is one of the most frequent malignant tumors in female and serious harmful to women's health and life.Its incidence is the second place of women's malignant tumors but is the first one in the developing countries and the second only behind breast cancer. In china,the prevalence of cervical cancer is 14.6Per10,000and is considerably highly level compared with that in other countries. At present check of cervical cell improves the early diagnose and medical treatment.The primary cervical cancer is 71.6% in five year's overall survival periods.but in carcinoma of cervix uteri is on the contrary. According to statistical number, About 35% Patient is palindrornia and not control behind treatment. Therefore it necessery to evaluate behind treatment frequently. Except for clinical pathology biomarker in traditional, Men is looking for a valuable caner biomarker for screeing , dianosis, and monitoing of cancer. KLK(Kallikrein) belong to the serine protease family of proteolytic enzymes,consise of fifteen number,map to chromosome 19q13.4 ,is controled by homour in human, and correleated to malignanant tumors.KLK14 is a member of the tissue kallikrein family, its cDNA spanning an area of 6349 bp of genotic sequence, is formed of seven exons and six intervening introns.That is almost indential in other KLKgenes.KLK14 is...
Keywords/Search Tags:Cervical cancer, KLK14protein, immunohistochemistry
PDF Full Text Request
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