| [Background and Objective]Sleep and respiration are important physiological phenomenoms for peoples and are the basement of humans life. Sleep is the essential conditions for revival physical strength, sustain psychological balance and physical health. Many physiological and psychological disfunctions could lead to diseases. OSA been seen as a serious clinical problem only in past 30 years, it could be divided into Central sleep apnea syndrome (CSAS) and Obstructive sleep apnea syndrome (OSAS). OSAS is the most common one of sleeping respiratory disease. The diagnostic criteria of OSAS is that patients had typical clinical syndrome such as snore and disorder respiration in sleeping time, excesses somnolence in daytime, apnea and Hyponea exceed 30 in 7 hours sleep time or AHI>5/h from the result of PSG. Patients had repeated apnea and Hyponea in sleep for the anatomic stegnosis, thickening and hyoerblastosis of soft tissue and increased collapsibility of upper airway. When the respiratory airflow was interruption at apnea the respiratory movement of chest and abdomen was still continue, and those are the character of OSAS. They had several changes of pathophysiological such as increased negative pressure in thoracic cavity, lower saturation of blood oxygen, higher PCO2, acidosis etc for the repeatedly apnea and Hyponea. Those lead to severe symptom such as rhythm disturbance of respiration and sleep, breath holding, increased ncturia, headache of daybreak, somnolence in daytime, decreased remembrance, unremitting weight gain, abnormality of psychology and intelligence and behabior, etc. OSAS patients often had complications of angiocardiopathy, gastroesophageal reflux, insulin resistance and disfunction of kidney, etc. OSAS had a higher morbidity and it was one serious problem for public health issue. Epidemiologic survey showed that the morbidity of OSAS was 2%-4% in middle aged peoples and it was higher in aged people, the mortality of severe... |
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