Long-term Result Analysis After Coronary Stenting In Patients With Multivessel Coronary Artery Disease

ObjectiveTo investigate the long - term results and prognosis after coronary stenting in patients with multivessel coronary artery diseaseMethodsTwo hundred and ninety - two consecutive patients who implanted selective coronary stent between October 2003 and December 2004 were followed - up by phone or clinic. Finally, there were two hundred and fifty - six patients who were investigated successfully, follow - up rate was 87.7%. They were divided into two groups. Group I included 104 patients with single - vessel coronary stenting, group II comprised 152 patients with multivessel coronary stenting , which included complete multivessel coronary stenting (67 patients) and incomplete coronary stenting (85 patients). Long - term results and follow - up outcomes were compared among the groups.ResultsMean follow -up duration were 17.4 ±3. 91 months in group I and 18. 2±4. 07 months in group II- There were no statistical difference between twogroups ( P > 0. 05 ). Procedural complication rate ( 4. 8% vs 3. 3% betweengroup I and group II , 3% vs 3. 6% between complete multivessel coronarystenting and incomplete multivessel coronary stenting) were also no statisticaldifference(P >0. 05 ). In whole, there were no statistical difference in nitrates cessation(26% vs21.7% ) and Clopidogrel duration(6. 1 ±2.67 vs6.8 ±3.44 months) between group I and group II (P>0.05). Compared with group I , group II patients had more recurrent angina (43. 4% vs 24% , P < 0. 01 ) , higher re - admission rate (24. 3% vs 13. 5% , P < 0. 05 ) , more cardiac event (12.5% vs3.8% , P<0.05) and lower improvement rate of cardiac function (85.5% vs 94. 2% , P < 0. 05). However, compared with group I , except longer Clopidogrel duration(7. 3 ±3.42 vs 6. 1 ±2.67 months, P<0.05) , patients of complete multivessel coronary stenting had no statistical difference in recurrent angina(32. 8% vs 24% ) , nitrates cessation (14. 9% vs 26% ) , re -admission rate( 16. 4% vs 13. 5% ) , improvement of cardiac function (92. 5% vs 94. 2% ) and cardiac event rate ( 10. 5% vs 3. 8% ) ( all P > 0. 05 ). In same, compared with group II , though there were no statistical difference in nitrates cessation(27. 1% vs 26% ) , Clopidogrel duration(6. 4 ±3. 37 vs 6. 1 ± 2. 67 months) (all P >0. 05) , patients of incomplete multivessel coronary stenting had more cardiac events (14. 1% vs 3. 8% , P <0. 05) , higher recurrent an-gina(51. 7% vs 24% , P <0. 01) , higher re - admission rate(30. 6% vs 13. 5% , P <0. 01) , lower improvement rate of cardiac function(80% vs 94. 2% , P <0. 01). And there were statistical difference in recurrent angina(51. 7% vs 32. 8% ) , re - admission rate (30. 6% vs 16. 4% ) , improvement of cardiac function (80% vs 92. 5% ) between incomplete multivessel coronary stenting and complete multivessel coronary stenting (all P <0.05).ConclusionCoronary stenting is safe and effective in patients with multivessel coronary artery disease, but long — term results and prognosis were worse than that of single - vessel coronary stenting. However, complete multivessel coronary stenting , which had similar results with single - vessel coronary stenting , was obviously superior to incomplete multivessel coronary stenting.