Clinical Analysis Of 148 Cases Of Cervical Cancer

Objective Cervical cancer(CC) has become a common gynecologicalcancinoma.80% of the new cases comes from the developing countries andabout 0.13 million cases exist in China.Recently the cases has made moreyouthful.The study of this disease has made many progresses in the cause,diagnosis,treatment and so on.But the reports of its application isdistinct.This study is to investigate its incidence,clinical situation,diagnosis,pathology character and treatment in our hospital and thedifference in different age segment.Methods We have analyzed hospital charts of 148 patients who hadbeen proved by pathological diagnosis in 2000,1-2005,8.Results Carcinoma in situ accounts for 4%,SC accounts for 91.3%,ADaccounts for 4%,mixed carcinoma accounts for 0.7%.The youngest is 25,the oldest is 75. The peak focus on 35-39, averaged age is 45.Besidesmedical examination discovering 12 cases(accounts for 8%),the shortestcourse was 2 days,the longest course was 8 years.Average time was 6.75months.Countryside patients were 95 cases,accounted 64%.7 cases hadsmoking history,the shortest course was 20 years,the longest course was 60years.Average time was 34 years.The symptom and physical sign of nonageCC shows atypism.Colporrhagia is the main symptom. Colporrhagia indifferent age is distinct.Contact bleeding focus on ≤35,accounts for68%.Irregular bleeding focus on 36～45,accounts for 42%.Post-menopausebleeding focus on ≥46,accounts for 37%.They have statistical significance(P<0.01,P<0.05,P<0.01).Cauliflower exogenism,dissipated ulcer,cervical canals' oncoides and hyperplasia are the typical signs of CC.Theexamination of Pap account for 43%,its false negative rate is 18%. Theexamination of TCT ,colposcope,cervical biopsy account for 1.4%,11%,100% respectively.Nonage CC account for 74% and advanced stage CCaccount for 26%.In which ⅡA ,0 and ⅠA stage was 43%,4% and 9%respectively. The soakage of muscular layer in post-pathology report was27%.The soakage rate of muscular layer in ⅠB ～Ⅱ B stage was 21%,32%,57% respectively.The comparison of Ⅰ B and Ⅱ B stage in muscularsoakage had statistical significance(P<0.05).ovary metastasis accounts for0.7%.The lymphaden metastasis is 21%. The lymphaden metastasis rate inⅠB～ⅡB stage was 17.9% ,18.3%,64% respectively. The comparison ofⅡA and ⅡB stage in lymphaden metastasis had statistical significance(P<0.05). The comparison of ⅠB and ⅡB stage had statisticalsignificance too(P<0.05).This study showed that misdiagnosis rate is0.7%.To take CC misdiagnosis for endometrial cancer.Conclusion The peak of CC focus on 35-39.HPV infection is the maincause of CC and its youthful. The symptom and physical sign of nonage CCshows atypism.Contact bleeding is the main symptom in nonage CCpatients;Post-menopause bleeding is the main symptom in senile CCpatients.Cervix cytology,vaginoscopy and histology exam were diagnosticprocedure.To reach early diagnosis and early treatment of CC.To cut downthe false negative rate of preoperative diagnosis,to raise the exact rate ofpreoperative clinical stage,to avoid misdiagnosis.To select correct treatmentplan in order to increase acromegalic existent quality. Conization of cervixrefers to the treatment of younger carcinoma in situ of cervix to retainprocreate function and diagnose and therapy of early microinvasion cancer.