Analysis Of Clinical And Pathological Relatived Factors About Radical Resection For Pancreatic Cancer

Objective: To compare the clinical and pathologic materials of two groups: radical resection and palliative resection for the pancreatic cancers in order to analysis the related clinical pathologic factors about radical resection.Methods: 77 cases of pancreatic duct adenocarcinomas which were treated with surgery and confirmed by pathology were chosen. According to the different surgery condition, we divided the 77 patients into two groups, 45 radical resection groups and 32 palliative resection groups. The patients' age, tumor size, differentiation grade, tumor staging, jaundice, back pain, abdominal pain, loss of weight, surgery time, blood loss in the operation, postoperative complications, postoperative survival and vascular encroachment between two groups were compared and analysised. Results: There were significant differences in tumor size, tumor location, blood loss in the operation, back pain, abdominal pain, TMN tumor staging, vascular encroachment between radical resection groups and palliative resection groups. We found patients' back pain incidence, TMN tumor staging, vascular encroachment were close relatived to the radical resection via Cox multiple regression analysis.Median survival time after radical resection and palliative resection was 16.0 and 8.0 months, respectively. The 1 year and 3 year survival rate after radical resection and palliative resection was 66.67%, 38.89% and 14.81 %, 5.56%, respectively. Conclusion: The risk factors of abdominal pain incidence, vascular encroachment rate and tumor TNM staging are associated with the pancreatic cancer patients for radical resection. The postoperative survival was significantly longer after radical resection, comparing to the palliative resection. Improvement of the veracity of early diagnostic in pancreatic cancer can raise the radical resection rate and prolong the pancreatic cancer patients' postoperative survival time.