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Imageological Research Of The Laryngeal Carcinoma

Posted on:2006-03-29Degree:MasterType:Thesis
Country:ChinaCandidate:B M ChenFull Text:PDF
GTID:2144360155970806Subject:Medical imaging and nuclear medicine
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Objectives: 1, To compare the pictorial quality of virtual endoscopy and mutiplannar reconstruction of different scan styles, for identiting the reasonable CT scan methods; 2, To explore the T stage value of CT and electronic laryngoscope before laryngeal carcinoma operation; 3, To compared the preliminary effect of CT and MRI during laryngeal carcinoma.Materials and methods : 28 cases with laryngeal carcinoma, male, age 4178(M=62.04). They had been performed the electronic laryngoscope examination and collected pictures. All had been patho-T staging after operation. 25 cases had been pre-and post contrast CT scan, among them, 6 were helical scanning, 2 plus MRI plain scan; 3 cases accepted CT plain scan only. 24 cases had been performed the virtual endoscopy and mutiplannar reconstruction by the CT raw and compared their pictorial qualities. Contrast analyzed the T staging of both CT and electronic laryngoscope pre- and post operation. The representations of CT and MRI were compared in laryngeal carcinoma.Results: 28 cases included 8 supraglottic cancers, 13 glottic cancers, 2 subglottic cancers and 5 transglottic cancers. Operation and pathology confirmed 1 case as tumor in site. There were 7 in T1, 6 in T2, 1 in T3 and 13 in T4. Before operation, electronic laryngoscope staging 7 in T1, 2 in T2, 5 in T3 and 2 in T4, 5 cases could not be staging by electronic laryngoscope; CT staging 10 in T1, 3 in T2 and 15 in T4. T staging sensitivities and specificities of electronic laryngoscope and CT in early period laryngeal carcinoma were 81.25% to 40.1% and 75% to 33.3% respectably; to advanced stage, the sensitivities and specificities turned to 18.75% to 59.9%and 75% to 66.7% respectably. During the early period laryngeal cancer, accurate rate of the electrolaryngendoscope and the CT were 81.25%and 69.23% respectively; but to the advanced stage, their accurate rate turned to 33.3% and 86.67 % . The accurate rate of CT combined with electrolaryngendoscope of T stage was 92.9%. The coefficient correlation between CT and operation was 0.916 (p<0.05). The observe index of MPR thinner slice group wasmuch better than direct manage group.MRI scan showed clear lesion in T4 case and some signs were superior to CT; Pictures of Ti case showed low SNR because of breath and both carotid arterial pulse, could not showed the lesion very good, its qualities were not as good as CT.Conclusions: Laryngeal carcinoma cases accept CT helical scanning with MPR postprocessing can show the lesion and its vicinal conditions better; CT combine with electronic laryngoscope can improve the T staging before operation; MRI staging to T4 is superior to CT while CT is superior to MRI in T\.
Keywords/Search Tags:Laryngeal carcinoma, T staging, electrolaryngendoscope, tomography, X-ray computer, MPR, MRI
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