Analysis Of TOAST Subtyping And Risk Factor Of Cerebral Ischemic Stroke In 89 Young Adults

Objective This work studied the etiological characteristics on the basis of Trial of Org 10 172 in Acute Stroke Treatment(TOAST)Criteria and risk factors of cerebral ischemic stroke in the young adults in this area and made a comparison with previous reports.Methods From January 2002 to December 2005,a total of 89 consecutive young cerebral infarction patients (15 to 45 years old) were admitted to the Department of Neurology in Qilu Hospital. The risk factors for stroke and the distribution of stroke subtype were studied. The vascular ultrasound MRA and angiographic findings of these patients were also studied.Results The sample contained 62 men and 27 women and men is significantly out of outnumbered women.The average age is 38.0 years old. Regarding stroke subtype, stroke of large-artery atherosclerosis in 18.8% of cases, small-vessel occlusion was diagnosed in 15.3%, cardioembolism in 14.1%, other determined etiology in 21.2%, and undetermined etiology in 30.8%. The 4 most common risk factors were hyperlipidemia (53.9%), hypertension (47.2%),smoking (27.0%), and alchol taking(24.7%). Seventeen patients (19.1%) had significant stenosis (50%) of the carotid (13.5%) and vertebral arteries (l.l%).Fourteen patients (15.7%) had significant intracranial stenosis with 14.6% in the carotid and 1.1% in the vertebrobasilar system.Premature atherosclerosis was the most common cause of intracranial stenosis.Conclusions 1.This study found that strokes of undetermined etiology were most common among the sample group, and a battery of extensive examinations is indicated to elucidate the etiology for further stroke prevention. 2.Stroke of largeartery stenosis is more than stroke of small vessel occlusion.3.The most common risk factors are hyperlipidemia ,hypertension,smoking,andalchol taking.lt is important to control these risk factors for prenvention of young ischemic stroke occuranceAHyperhomocysteinemia is an undependent risk factor for young ischemic stroke,so it should be cared.5.1ntracranial stenosis is more common than extracranial stenosis in both the carotid and vertebrobasilar systems.