Study On Relationship Between Syndrome Types And Serum Lipids, Blood Glucose, Blood Pressure And Nervous Impairment In Patients With Acute Cerebral Infarction

Objectives: To detect the serum level of triglyceride(TG), total cholesterol(TC), low-density-lipoprotein-cholesterol(LDL-C), ApoA1, ApoB, ApoB/ApoA1 and the fasting blood glucose(FBG), blood pressure(BP) ; calculate the score of nervous impairment (SNI); so as to investigate into the relationship between syndrome types of Acute Cerebral Infarction (ACI) and the four aspects indexes: the scores of nervous impairment, serum lipids, FBG and BP.Materials and methods: 104 patients with ACI were collected, among which 56 were male and 48 were female. The average age was 70.97±9.55years(aged 43-89 years). All were divided into five groups:sudden excess of liver -yang group(SELY,18 cases), wind-phlegm and blood stasis group(WPBS,28 cases), phlegm-heat and sthenia of fu-organ group(PHSF, 23 cases),qi deficiency and blood stasis group(QDBS,17 cases) and Yin-deficiency and wind generating group (YDWG,18 cases) . Measure the onset blood pressure and calculate SNI .Detect serum level of TG, TC, LDL-C, ApoA1, ApoB andFBG the next day onset.Results: 1. Among all of the syndromes of ACI, the highest proportion was WPBS syndrome and the second was PHSF syndrome.The highest SNI of patients with ACI was in the group of PHSF, and the lowest one was in the group of QDBS. The difference between them was significant (P<0. 05) , while other groups did not have markable difference (P>0. 05) .2.The highest serum level of lipids was WPBS group, and followed by PHSF group; The difference between WPBS group and every other groups was significant (P<0. 05, P<0. 01) ; so as between PHSF group and QDBS group, YDWG group (P<0. 01).3.Among all groups, level of ApoAl in WPBS group was the lowest,while ApoB and ApoB/ApoAl was the highest, followed by PHSF. There was significant difference between WPBS group and every other groups (P<0. 05, P<0. 01).4.When referring to blood glucose, level in PHSF group and YDWG group were higher than other groups. While there was no significant difference among them (P>0. 05).5 Our analyse on blood pressure show that level of BP in SELY group was Na 1 and PHSF group was Na2.The difference between them was significant (P<0.05) . that level of BP in SELY group was markedly higher than that of WPBS group, QDBS group, YDWG group (P<0.01) . And that level of BP in PHSF group was markedly higher than that of WPBS group,QDBS group, YDWG group (PO.01) .6. The SNI in higher-glucose group was markedly higher than that of normal-glucose group (,P<0.01). Correlation between SNI and level of glucose was medium (r=0.522), and the relativity was markedly (P<0.01). While there was lighter correlation between SNI andlevel of serum lipids and BP(r<0.40).Conclusion: 1. the stroke acute stage was prominent by the sthenia symptom.,Phlegm and stasis blood may be the primary pathlological products and pathogenesis factor., sthenic-heat of yangming possibly aggravate ACI.2. There was serious lipids, glucose disturbance and increase of BP in patients with ACI.3. The level of serum lipids and BP were relative with TCM types of ACI, so they can be objective index for ACI.4. The level of blood glucose can reflect the severity of ACI., while the level of serum lipids and BP were relative with ACI. as risk factors, But whether it can reflect ACI patients condition still waited for further studies.