Structure Of Lumbar Vertebral Endplate And Its Biomechanical Properties And Clinical Significance

Objective: To study the structure of anatomy and histology on the lumbar vertebral endplate(LVE) and biomechanical properties,and to evaluate clinical significance.Methods: 1.The thickness of lumbar vertebral endplate(TOLVE) beingmeasured: The thickness of the anterior, center, posterior in the superior and inferior LVE along sagittal plane was estimated by direct measurement from 30 lumbar vertebraes, to find anatomical properties. The histology of LVE was studied by light microscope to clarify its importance in the procedure of lumbar disc degeneration.2.Biomechanical experience:(1).Six human cadaveric lumbar spinal specimens( L1~S1)were divided into six groups: intact FSU(A), unstable FSU(B), preserving intact VE with implanting threaded fusion cage(TFC) FSU(C), excising 1/2 VE of centrical region within superior and inferior VE with implantingTFC(D), excising all superior and inferior VE with implanting TFC(E). Spinal ROM were determined by testing in different groups.(2).30 lumbar vertebral specimens(L1~L5)were divided into three groups: Preserving intact superior and inferior VE(A), excising 1/2 VE of centrical region within superior and inferior VE (B), excising all superior and inferior VE (C).Anti-compressive loading(ACL) and deformation were determined by testing in three groups. To evaluate biomechanical properties of LVE. 3. clinical significance: In case with lumber interbody fusion, the group of preserving LVE(A) later was compared with the group that without preserving LVE(B) earlier, to analysis the importance of preserving LVE.Result: 1 .TOLVE measurement:In each lumbar vertebrae TOLVE had nosignificant differience between the central region of superior and inferior VE(P>0.05),had no significant differience between the anterior and posterior in the inferior VE(P>0.05);in L4 and L5,TOLVE there were not significant differience...