～(27)-Al-NMR Studides Of The Interaction Between Aluminum And Different Kinds Of Biologic And Organic Ligands In Tea

Aluminum is not a kind of dispensable element to human being. Recent scientific researches have revealed that there may lie some kind of direct or indirect relationship between aluminum and inducement of Alzheimers disease, Parkinson's disease, and so on. So eliminating excessive aluminum in body is beneficial to health. In present, the main method is that the complexation of Al(â…¢) by strong organic ligands is applied to reduce the overload in human body, and then the chelate compoud is expelled from body by metabolism. Tea polyphenols is a excellent ligand, but there are lack of detailed reports about the fine structure of this kind of chelate compound. So the interaction between aluminum and different kinds of biologic and organic ligands in tea is studied to find out the mechanism of detoxification more deeply, and then develop a sort of high effective drug.27Al NMR as a fast, direct and non-destructive detective method was used to study the existent forms of aluminium in aqueous tea extract. The rules and characteristics of the coordination of oxalic acid and malic acid with Al(â…¢) were concluded, according to which it was confirmed...