| Objective: To observe the clinical effect of the treating method of reliving depression and clearingheat, which comes from Treatise on Exogenous Febrile Disease, on anxiety. Minor Decoction of Bupleurum in combination with Decoction of Gardeniae and Sojae Praeparatura was applied in the study.Methods: 80 cases of anxiety were divided randomly into treatment group treated with Chinese herbs, which were made into scientific form, and control group treated with Alprazolam, 0.5mg each time, thrice daily. The therapeutic course lasted for 6 weeks.Results: (1) According to HAMA, significant difference was observed in both groups before and after treatment (*P<0. 05, **P<0. 01 respectively, byt-test). As to the decreased value, There was no significant difference between 2 groups(P>0. 05, by x test). (2) According to HAMA factor grade, significant difference was observed in both groups before and after treatment (*P<0.05, **P<0.01 respectively). As to the decreased grade after treatment, There was no significant difference between 2 groups (P>0. 05, by X* test). (3) According to SAS, significant difference was observed in both groups before and after treatment (*P<0. 05, **P<0. 01 respectively, by t-test). As to the decreased value after treatment, There fas no significant difference between 2 groups(P>0. 05, by x test). (4) As to the decreased value of GGI after treatment, There was no significant difference between 2 groups(P>0.05, by X test). (5) After treatment, there were less side effects in the treatment group than in the control group (P<0. 01) such side effects includes fatigue, dry mouth, bitter mouth, dry. stool, dizziness, headache, nausea, tiredness, blurred vision.Conclusion: The effect of Chinese herbs of relieving anxiety and clearing heat is equal to that of alprazolam. This treating method is better for corporality anxiety. |