The Clinical Study Of Jibi Decoction On Ankylosing Spondylitis In Active Phase

This study, baseing on the theory of TCM and combination of Traditional Chinese with western medicine , Systematically and intensively explores the etiological factors and therapeutic methods for ankylosing spondylitis(AS) in active phase from both theoretical and clinical aspects. The research considers the Wet heat and stasis toxin and the blocking of kidney and Du Mai as the main causes of AS in active phase,and accordingly adopts eliminating Wet heat toxin, activating blood and strengthening kidney and Du Mai as the main therapeutic method .In the study ,JI BI decoction is taken as the test group with Huo Ba Hua Gen Tableas as control one and with 30 subjects in each group . The results show that the controlled and effective rate in test group is 63.33% with 26.67% in control one (P < 0. 01) .But the total effective rate shows no difference in two groups. In the aspect of of eliminating symptoms improving laboratory index and antidestruction of bone, the test group is superior to the control one (P< 0.01 or P< 0. 05) . The mechanism might be relate to anti-inflammation, relieving pain, regulating immunological function , improving hemorheological index and bettering microcirculation, etc. In such view ,it treats AS effectively in poly-side.