Clinical And Experimental Research On Treating Post-Operational Pain Of Mixed Haemorrhoids With The Ointment Of Gang Tong Ning

As a kind of familiar symptoms in clinic,mixed haemorrhoids post-operational pain is always difficult to be treated.Therefore,clinical doctors pay more and more attention to it.Thinking in traditional Chinese medicine(TCM),such kind of pain was mainly caused by operation or ligation, which damage physique-vessels, channels and collaterals in that qi was blocked in the part of channels and could not become unimpeded,so the qi-blood became stagnation,meridians and collaterals impassable, the patient ached.There would be little effect if you treat the post-operational pain only throuth removing pathogenic heat and toxic materials,dispelling wind to promote diuresis,subduing swelling and alleviating pain except of removing blood stasis and promoting the circulation of qi.which is the key to the problem. 63cases was divided randomly into two group.The treatment group(including 32 cases) was treated with the ointment of Gang Tong Ning(GTN),and among the control group (including 31 cases) with Jiu Hua Suppository(JHS).The efficient rate of treatment group was 90.63%, as a contrast, the control group 61.29%.There existed marked difference between them(P<0.05). Meanwhile, the integral calculus also has obvious diffierence between pretreatment and post-treatment(P<0.05).For the objective of probing the pharmacology of GTN,authors investigated the influence of GTN on mouse torsion reaction caused by acetic acid injecting from abdominal carity,on mouse tail root where paining caused by stress, on the swell experiment to the big rat foot metatarsus, the influence on small rat ear outline tiny circulation, compared with JHS. Results showed that inhibition rate of mouse torsion reaction was 47.32% caused by GTN which prolonged latent period of pain threshold,obviously repressing swelling responds to big rat foot metatarsus caused by albumen, and had the obvious ameliorative function to the tiny circulation of small white rat.lt suggested that GTN had significant effect of analgesia and anti-inflammation,improving tiny circulation. From the clinic and experiment,it showed that GTN was effective on mixed haemorrhoids post-operational pain treated from stagnation, by removing blood stasis and promoting the circulation of qi,clearing out the obstruction in the channels to arrest pain.