| objective: to discuss the distal embolisms and its effect on the tissues perfusion after the dissolution of superior artery and evaluate the technique of angiography using which to recognise the microembolisms. Method : choose randomly one of the superficial femoral of rabbit as test group, which were stimulated using electric current outside vascular wallto form a thrombosis model , the other as control . r-SAK was injected through vein to restore tissues blood flow . angiography was used to find out the changes and abnormalities of distal arteries before and after thrombolysis . the observation points were located manually on digital subtraction in the legs of both groups .the gray scares of the observation points were measured with software , and the densities of contrast medium in tissues were then calculated three time by two men respectively . the densities of contrast medium in tissues were arranged and curved according to time . we compared the densities of contrast medium in tissues of both groups by means of autocontrol before and after the superficial femoral thromboses dissolved.Results: of 8 animals of test group , we found 17 filling abnormalities through angiographic photos , and 4 embolisms by pathologic examination, while no abnormality was found in the control (P<0. 05). the measurement of the densities of contrast medium in tissues: no significant difference was found between two groups before thromboses forming ; after the formation of thromboses of the superficial femorals , the blood flow ceased and tissues did not display in the test group ;when the thrombosesdissolved ,the blood flow restored but the densities of contrast medium in tissues of test group were much lower than those of the control group Conclusion: after thrombolysis .embolism is a common phenomenon and it can reduce the perfusion of tissues;angiography can be used to find out small embolism ;and the densities of contrast medium in tissues can reflect tissues blood reperfusion . |
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