Measurement Of Carotid Artery Lesion With Plasma Lipoprotein And Cerebrovascular Disease By High Resolution Ultrasound

Objective: Evaluate the intimal-medial thickness(IMT) and plaques of double sides common carotid artery , and the bore as well as the hemodynamics of carotid and vertebral arteries including SPV,EDV,PI,RI, et al and the correlation of carotid arteriosclerosis with plasma lipoprotein.Method:Btween January 2000 and April 2003, 91 patients including 41 patients with and 50 without hemispheric infarction were performed with HDI 3000 color Dopple ultrasound examination using combined B-mode ultrasound, two-dimensional color Dopple flow imaging and power Dopple imaging examination include measurement of CCA - IMT, the hemodynamics of carotid and vertebral arteries(CCA,ICA,ECA,VA) index,the sites of plaque mean-while plasma Lipoprotein and apolipoprotein were tested. Result:①The intimal-medial thickness of carotid thickenedin the position of trunk and its tributaries thickened in patients with hemispheric infarction as compared with those in the controls.Atherosclerotic plaques of carotid arteries occurred in 32 cases(32/41, 78.0%).②The prevalence of plaqueincreased from the lowest to the highest quintile of IMT(linear trend:P＜0.01)and the mean IMT was lower in subject without plaque than in subjects with plaques (0.64±0.12mm vs 0.83±0.16, P＜0.01). ③Compared with controls, the plaque of common carotid artery and arteriae carotis interna widened significantly, and the end-diastolic velocity(EDV) and the time average velocity(Vmean) were evidently decreased and the resistive index(RI) as well as pulsatilityindex(PI) increased in carotid and vertedral arteries.Carotid arteriosclerosis was inversely correlated with apolipoprotein(apoAI).Conclusion: The atherosclerosis of carotid and vertedral arteries was related to the incidence of hemispheric infarction and the soft plaque in carotid arteries might be one of the potential cause for hemispheric infarction; Increasured in the CCA are clearly related to atherosclerotic plaque in the ICA; In carotid arteriosclerosis,apoAI result a more significant reduction than it does normally.Besides the two non-injury test techniques,it has clinicad value in prediction and treatment of cerebrovascular disease.