Values Of The YF-1XGYD Device In Assessing Arterial Stiffness

Objective:This study was designed to assess the immediate test repeatability of arterial stiffness index measured by YF-1XGYD device and evaluate the device's value in clinical application.Method: YF-1XGYD device was used to obtain the index of brachial arterial stiffness(ASI).50 healthy subjects were measured static arterial stiffness at 0,3,10 and 20 minute ,respectively when the process began after fifteen minute period rest. Arterial stiffness of 420 healthy subjects which were divided into four groups every 15 years old from twenty to seventy-five years old were investigated .. The relationship between ASI and SBP,DBP and PP of both healthy and hypertension subjects were analysised.ASI of four groups of 125 hypertension patients at different risk degree(low,middle,high and very high) were compared to evaluate the value in assessing cardiovascular risk.The relationship between Framingham score and ASI were analysised.Result: (1)There was good repeatability of ASI if the interval time between every two measurments was achieved to five minutes.(2)ASI of healthy populations increases with age gradually .After the age of 60 there was a more pronounced increase of ASI.The value of ASI of man in 60-75 years old group was 102,while value of woman was 109.(3)There was positive correlation between ASI and SBP,PP,DBP.The correlation coefficient(r) was 0.71,0.67,0.42 ,respectively .(4)ASI increased with the risk degree in hypertension patients. And there were no significant difference in every two group of four.ASI of ninty-four hypertension patients with normal blood pressur after treatment decreased greatly comparing with the value before treatment.Among the four groups after anti-hypertnsion therapy,the value of ASI of the very high risk group was greater than the other three groups.(5)the higher the Framingham scor,the greaterthe value of ASI no matter man or woman. Conclusion:The repeatability of the device of YF-1XGYD is good.Age and blood pressure are the main clinical determination of ASI.There is a good positive relationship between ASI and the risk degree of hypertension. The value of ASI increases with the Framingham score. The device of YF-1XGYD is a noninvasive, relatively low cost,ease of use,and acceptability to patients.It is can be used in clinical study,although the full clinical impact of the measurement is not yet clear.