Clinical And Experimental Research On QiangXinFumai Drink In Treating Slow Arrhythmia

By using the way of traditional Chinese medicine (TCM)thought , this article explores deeply the cause and mechanism, principle and method of therapy of Slow Arrhythmia from three aspects: theory, clinic and experiment, so as to find the effective recipe of creating. This research puts forward the pathogenetic hypothesis, which is deficiency of yang of heart and kidney, blood stasis and abstraction of channels. This subject regards warming yang and promoting Qi, invigourating blood to remove channel obstruction as principle of therapy. According to this , herbs are choosed and recipe is made up , then the QiangXinFumai Drink is made by using modem process. 46 slow arrhythmia patients were treated by taking QiangXinFumai drink, meanwhile, another 26 slow arrhythmia patients were treated by taking Xinbao pill comparely as conterol. Results showed: QiangXinFumai drink group got 60.87% prominent effective rate in treating slow arrhythmia, with a total effective rate of 91. 30%, which was prior to the control evidently (P<0. 05). Furthermore,46 patients by taking ^QiangXinFumai drink was prior to the control evidently in the changes of resting heart rate (RHR), intrinsic heart rate (1HR), dynamic electrocardiography(P<0.01 and P<0.001). The QiangXinFumai drink can improve the symptoms of whole body, function of left ventricle , put right the metabolism disorder of blood lipid.reduce blood viscosity. Animal experiment indicates: The recipe can increase the heart rate of normal wakeful rat. And the recipe can inhibit the albino rat' s heart from slow arrhythmia caused by proprandoli and Isoptin obviously. It has marked effects of increasing heart contractility. The research results proved: deficiency of yangof heart and kidney, blood stasis and abstraction of channels is the important mechanism of slow arrhythmia; so warming yang and promoting Qi, invigourating blood to remove channel obstruction is an important therapy to slow arrhythmia. QiangXinFumai drink treating slow arrhythmia has not only prominent clinical curative effect, but also substantial pharmacologic and potent fundament. It's proved that this drink can treat slow arrhythmia through several links and target points , possessing comprehensive therapeutic effects. Jt' s an effective recipe of treating slow arrhythmia. This research deeps the TCM comprehension to mechanism of slow arrhythmia; puts forward new research way, therapy and recipe; does beneficial attempt to enrich the pathology and therapeutics of slow arrhythmia.