Study On Ultrasound In Monitoring Hemodynamics Of Kidney, Liver And Large Vessels In Hemorrhagic Shock Rat

Objective: The aim of this study was to evaluate hemodynamics of kidney, liver and large vessels in the hemorrhagic shock rat by Ultrasound. Methods: Ultrasound was performed before the hemorrhagic shock, 30-90 minutes in hemorrhagic shock stage and within 24 hours after reperfusion. Methods of examinations include: two-diminsional ultrasound(2DUS),color velocity imaging(CVI) and Pulsed wave doppler(PW). Index of observation as fellows: Renal size and diameter of portal vein(PV) and inferior vena cava (IVC) were measured by 2DUS. Blood perfusion of kidney and liver was evaluated by　CVI. PW was used to measure the peak-systole velocity (Vmax),end-diastolic velocity (Vmin),mean velocity (Vmean),resistive index (RI),pulsitive index (PI) of renal and hepatic artery, portal venous volumetric flow(PVQ) and velocity of renal and PV and Ao and IVC and femoral artery and femoral vein. Results: In the hemorrhagic shock stage, there were no significant changes in 2DUS of renal and liver. Distribution of blood stream in the kidney and liver decreased. Blood perfusion of renal cortex disappeared. Renal arterial Vmax,renal and hepatic arterial Vmin, Vmean, PVQ, velocity of renal vein and PV and IVC decreased significantly, and RI,PI of renal artery and hepatic artery increased significantly. But there was no significant difference in hepatic arterial Vmax, and the velocity of Ao,femoral artery and vein after hemorrhagic shock. In the reperfusion stage, Distribution of blood stream in the kidney and liver increased; velocity of renal and hepatic artery and IVC increased significantly; RI, PI of renal and hepatic artery decreased significantly. There was no significant difference in portal venous velocity and PVQ. Conclusion: Ultrasound can accurately monitor hemodynamics of renal, liver and large vessels in hemorrhagic shock rat.