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Analysis Of The Clinical Therapy Effect In Acute Ischemic Cerebral Disease

Posted on:2002-03-05Degree:MasterType:Thesis
Country:ChinaCandidate:Z J LiFull Text:PDF
GTID:2144360032950342Subject:Neurology
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The Ischemic Cerebral Disease has defied the considerable efforts of medical science to find an effective treatment and remains the high disabled and cause of death in the world today, Therefore , make it even more important to find an effective treatment. To investigate and summary of the clinical characteristics of 2050 cases hospitalized which acute ischemic stroke in the past decade with MESSS .6 groups can be classified according to the treatment within 3 weeks. Haparin,low-molecular heparin,urokinose,and antiplatelet groups have more effective outcomes than the others groups.Over 70 percent of patients recoved to full independend function, such as ,haparin,Urokinose group were significantly decrease stroke scales than antiplatelet group. The score was decreased as the onset of symptoms to strok treatment time was delaied.which was not significant difference in the 6 group within 6 hours .The clinical advantage of every group was decrease as the onset of symptoms to stroke treatment time over 6 hours. The outcome of 6 groups was not significantly difference in the mild and moderate neurological deficit. except antiplatelet group in the moderate. Urokinose, and defibrasw group were more clinical advantage than antiplatelet group in the severe neurological deficit. The rates of progression of stroke ,major of stroke, and intracerebral hemorrhage were 20.87%, 9.7 1%,and 5.66%,and respectively , The indepentend rates of which were 45.56%, 56.28%,and 59.48%,and respectively ,the mortality of which were 6.3 1%, 12.06%,and 4.3 1%,and respectively .The incidence of intracerebral hemorrhage in 118 patient with Haparin treatment was 10.15%,which significant higher than that 6 of with fowmolecular heparins trCtant,sPChay in yOunger and o1dersubjects.A significant difference was observed betwCen the carotid 8rtCrygrOuP (87.59%)and the vertebrobasilar artery grOuP(91.16%). UroldnosegrOup was more c1inical Anproved in the carotid artery grOU(2.38o/othan in the vertCbrobasilar thery group.HaParin grouP, lowmoleCular heparin grOU,and uroklnose grouP withtrCfornt Transient Ischendc Att8Cks mp and lacunar have moreimproved than other 3 grOU, espicmp haParin grouP a lowerdevelopment cerebral infartion (12.22%).The cerebral embo1ism occurred high major of strOke(33.9.%),andintracerebral hemorrhage (38. 10%)and dedth(6.55%).The ats of progression of strOke, major of strOke, and intraterebralhemorrhage in the cerebral thrombosis were 22.33%, 1O.33%,and2.95%,and respective1y.The outComes of haParin grOUp and urohaosegrOuP were more significat differences than that of antiPlat6let anddefibrasw grOup.AnticagUlant trCtant and uroboose trCinent are beneficial andsignificant better neuro1ogical improvement.
Keywords/Search Tags:Analysis
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