Objective: To study the efi t of alanyl-glutarnine (Ala-Gin) suypiemented W parenteml nutiiiion (JPN) Cu iutein metabolism, liver and kkkney lhnction, cell knmo1oge, bacterial Uanslocation, intesliml rnucod sUucture, giiniila&u dssues on wwnd in homed rats. Methods: Thitty-three SD mis were divided into three gx equally chow up, conventional ThN gxq (convention gum) and Ala-Gin supplemented TPN gmup (Ala-Gin gmop). The chow gwup received standatd rat chow, The two TPN gixtps rats that were placed a cenUil verxus catheter and suljected to 30 o ThSA 1110 brn received isocalcric (78(kl.kg d and i.mitrogencus (1.8gNkg d 480/a of nitingen s sp1ied with Ala-Gin in Ala-Gin gjq) ThN fix 7 days. I\litmgen halance and cinnulated nitrogen halance were monitored. At the end of ThN, senim td nein (TP), albLllnin (ALB), preallumin (PAB), transnin ([RE), Gin in rnusele, liver and kidney ftncfion lxnalneters ,T lympiiocyte suhts were monitored. Jejiuial niuccxsal meq*iological changes were iv& v4di light niicnscqy and elecinru micIuseopy. The densities of capillary vessels and fibiublasfs oftdaticu tissues on wound wet observed v4th light mictoseqy. Results: The iun PAI3, ThF and GIn level in rnuseie in Ala-Gin gonp were sigpificantly higher than those in convention jx (P |