Object: To discuss the poisonous mechanism of alcohol in cerebral, the effects of alcohol exposure on female mouse's cerebral cortex and hippocampus were observed. Methods: the different density of alcohol (12.5%, 25% and 50%)were irrigated to two months female mouse, the effects of cerebral structure and function were analyzed in fixed quantity by using Morris water labyrinth, immunohistochemistry, electron microscope, and pathologic image analysis system. Results: OMorris water labyrinth incubation period obviously extended in high and middle density group (p |