| Objective:To study the pharmaceutical characteristics of compound enrofloxacin injection including its pharmacodynmics, safety, prescription and preparation.Methods:1. Antibacterial activity of combination use of enrofloxacin and colistin sulfate was detected by measuring of the fraction inhibited concentrations (FICs). Antibacterial activities of compound enrofloxacin injection were studied in E coli, salmonellae, pasteurella and staphylococcus aureus in vitro and in piglets with white and yellow diarrhea in vivo.2. Stability of compound enrofloxacin injection was detected to evaluate the rationality of its prescription and preparation.3. Acute toxicity to mice and subacute and chronic toxicity to rats were observed to evaluate the safety of compound enrofloxacin injection.Results:... |