| Purpose:: This paper organized and analyzed literature related to infertilitythrough statistics software and the data mining method to summarize its syndromedifferentiation and treating regularity from the kidney.Providing theoreticalbasis for clinical treatment of sterility.Material and method: Collecting Chinese medical record class literatureabout sterility tally to inclusion standard in CNKI from1972to2012integratesthe, using the excel software to establish database. Frequency analysis, factoranalysis,and connection rule analysis are conducted with SPSS and the Clementinesoftware in the XP system platform.Results:1According to frequency analysis, in the administration of infertility, theproportion of tonic medicine is the largest, followed by regulating Qi medicine;drugs for infertility are primarily go into the kidney.Syndromes with the highestproportion of kidney deficiency.2Factor analysis presents4commonly combinations of different pathogenicmechanisms.F1focused on nourishing liver and kidney; F2centered on regulatingqi, eliminating stagnation and dampness; F3focused on warming kidney yang; F4dealt with both reinforcing and reducing, but mainly tonifying kidney yin.3Association rules analysis put forward18associated strong combination oftwo-drug,93associated strong combination of three-drug,51combination oftop four Chinese Medical Association,5associated strong combination offive-drug.4Association rule analysis of infertility and the Zang-Fu position revealedthat infertility organs positioned primarily in the kidney. 5Associated rules analysis between HF drug and syndromes results displayedthat there are6HF herbs having strong association with kidney deficiency, and10with kidney Yang deficiency, and7with kidney yin deficiency,7with liverand kidney yin deficiency,5with kidney deficiency and blood stasis,6withspleen and kidney deficiency.6Association rule analysis of2kinds of medicine and syndrome showed that thereare5having strong correlation with the kidney deficiency syndrome;7withkidney-Yang syndrome;8pairs with kidney-Yin deficiency;6with liver-kidneyYin deficiency.7Association rule analysis of three Chinese medical and syndromes showed that11group of drugs have combinations with kidney deficiency;11groups withkidney-Yang;17groups with the kidney Yin deficiency;13groups with theliver-kidney Yin deficiency.8Associated rules analysis of4-drug and syndrome showed that13groups areassociated with kidney deficiency;7groups with the kidney Yin deficiency;8groups with the liver-kidney Yin deficiency.9Association rule analysis of5kinds of medicine and syndrome of resultsshowed that1group drugs are associated with kidney-Yang deficiency;2groupswith the kidney Yin deficiency,1group with Yin deficiency of liver and kidney.Conclusions:1Through the analysis of high frequency drug, as well as on drug classificationand analysis of syndromes, we inferred that mechanism of infertility mainly inthe kidney,accompanied by qi stagnation and blood stasis. Treatment based ontonifying the kidney,supplemented by regulating qi and activating blood throughassociated relationship between five Zang-organs.2Frequency analysis for drugs display that most of the high-frequency drugsto treat infertility go into kidney, with the effect of reinforcing kidney andessence; in terms of classification of syndromes, infertility is primarily on kidney deficiency. Treating infertility from kidney has practical andtheoretical significance according to data analysis.3Factor analysis showed that when treating infertility, method of tonifyingkidney is commonly used, and often supplemented by regulating Qi, activatingblood, invigorating the spleen and clearing dampness, suggesting thatpathogenesis of infertility is based on of kidney deficiency, mostly of Qistagnation and blood stasis syndrome.4Associated rules analysis of viscera position, single drug, and paired drug,and drug groups and types displayed that relationship between infertility andkidney belongs to strong association, and all the strong correlation herbs arebased on reinforcing kidney and essence, prompting that kidney essencedeficiency is the pathological foundation of infertility.And reinforcing kidneyessence is considered to be the major method in treating infertility. |