Study On TCM Syndrome Characteristics And Syndrome Distribution Of Jaundice

Purpose:This study aimed to review the ancient and modern jaundice literature, retrieving the jaundice syndrome type and the related literature in the nearly20years, to conclude that the evidence of TCM jaundice element type characteristics and the distribution, and provide guidance for clinical specification of jaundice syndrome differentiation.Methods:1.Literature research:Reviewing the ancient and modern literature, understanding of ancient and modern jaundice disease classification, characteristics and research progress of etiology, pathogenesis and syndrome differentiation and treatment.2. From the hownet, ten thousand party and VIP literature database selection about jaundice syndrome differentiation of the literature collection in recent20years, to extract the syndrome and syndrome factor and set up the database, to justify the use of statistical methods for frequency and syndrome factor distribution, to cluster analysis and explore its regularity. Finally, to integrate analysis of the statistical results combining with the basic theory of TCM.Results:1. Literature research:reviewing of ancient and modern literature, understanding of ancient and modern of jaundice disease classification, pathogenesis and syndrome differentiation and treatment. On the classification of disease and neijing jaundice disease is put forward for the first time, and the first from synopsis jaundice was divided into five jaundice, after "on the pathogenic hou" jaundice was divided into28, the peaceful holy benevolence formulae, jaundice was divided into "thirty-six yellow","st. Xavier always record the points" nine jaundice ", the "thirty-six yellow", will appear all sorts of jaundice disease are included in them. On the etiology and pathogenesis, past dynasties doctor knowledge of the etiology and pathogenesis of jaundice mainly includes:damp heat, dampness and heat, dampness, plague poison, booze, tired, from several aspects, such as bile leakage which is more hot and humid, it put forward by neijing, subsequently involved in almost every dynasty in damp heat jaundice theories content. The pre-qin period, mainly dominated by damp and hot, and put forward the stasis hot, cold dampness, drinking, diet yellow view; Sui and tang dynasties.’s nest on the basis of predecessors’emphatically put forward the plague poison yellowing, and jaundice is infectious; The period of song, jing and mainly zhu’s "hot"; During the Ming and qing dynasties, Zhang Jiebin proposed "bile leakage yellow" is the innovative understanding for jaundice etiology and pathogenesis. In terms of treatment based on syndrome differentiation, zhang zhong jing in han dynasty put forward "five jaundice syndrome differentiation" and "six-channel differentiation", created the beginning of jaundice syndrome differentiation; Northern song dynasty and Korea contained and propose Yang and Yang syndrome differentiation, huang huang has jaundice syndrome differentiation system preliminary formation; Jinyuan period by creek "damp heat syndrome" is put forward for the first time, how to guide the clinical syndrome differentiation in hot and humid weight; Enrich and improve the system of jaundice syndrome differentiation; To the Ming and qing dynasties, the doctor is mainly inherited and improve the predecessors’theory of syndrome differentiation and jaundice treatment based on syndrome differentiation system development peak; Modern physicians are mainly explore and research the ancient jaundice syndrome differentiation theory, and combined with modern medical knowledge, type of jaundice syndrome differentiation treatment.2. Data analysis:Reading312references and including2209patients with jaundice meeting the requirements, including a total of46justification of norm type, get21jaundice syndrome factor, including disease syndrome factor and disease resistance syndrome factor of8and13respectively. Through frequency analysis, included in the jaundice seven often witness in all cases of the score for the hot and humid type indicates sheng (36.12%), liver (8.33%) of damp and hot, change the type (4.75%), blood stasis, stop product type (4.57%), liver and kidney Yin deficiency type (4.16%), toxic heat flourishing type (4.07%), cold dampness blocking type (3.85%); Disease syndrome factor in total disease bits of the score for the liver (42.89%), spleen (25.77%), bile (14.94%), renal (8.48%), stomach (6.87%), colon (0.89%), table (0.08%), half exterior and half (0.08%). Of disease resistance syndrome factor in total disease score from high to low in turn is hot (32.55%), moisture (31.82%), and qi (8.82%), qi deficiency and blood stasis (8.36%),(5.79%), cold (4.24%), poisoning (2.62%), Yin deficiency (2.47%), Yang (1.38%), massive hemorrhage (0.99%), drinking (0.63%), closed (0.27%), sputum (0.05%). Through clustering analysis, in justification of jaundice common element clustering, wet and hot for a class; Liver, spleen, and qi stagnation and blood stasis gathered for a class; Qi deficiency, Yin deficiency, poison, kidney, stomach, cold, bravery for a class, may indicate that three kinds of the basic pathogenesis of TCM jaundice unit. Conclusion:(1) The ancient and modern knowledge of jaundice is a process of gradually deepening and perfect, jaundice concept is not the same, etiology and pathogenesis is still is given priority to with damp and hot, syndrome differentiation type diversity, not form a unified standard.(2) The literature research of jaundice in main card type:dampness heat indicates sheng, courage syndrome, change the type and blood stasis stop product type, liver and kidney Yin deficiency type, toxic heat flourishing, cold dampness blockage.(3) The main syndrome factor, a total of21jaundice, including disease syndrome factor including the liver, spleen, gallbladder, kidney, stomach, large intestine, tables, half exterior and half; Disease syndrome factor including heat, wet, and qi stagnation and blood stasis, qi deficiency, cold, poison, Yin deficiency, Yang deficiency, blood deficiency, drinks, closed, phlegm.(4) Certificate knew characteristics:liver is the key of jaundice disease syndrome factor; Hot for jaundice major disease syndrome factor; Hot and wet two syndrome factor combination to jaundice; Blood stasis is one of the important causes jaundice happens; Factors, give priority to with real is the pathogenesis characteristics of jaundice.