Clinical Study On Treatment Of Purpuric Nephritis By Syndrome Differentiation

Objective:The paper aims at playing the advantages of traditional Chinese medicine on syndrome differentiation and treatment and creating the prevention and treatment of purpura nephritis overcast by setting shaoyin dialectics with distinctive features, which is to form a unified and standardized clinical diagnosis and treatment of purpura nephritis and given priority to shaoyin syndrome differentiation of purpura nephritis clinical diagnosis and treatment plan eventually.Methods:72cases of in-patient in Sichuan province people’s hospital of pediatrics outpatient service and Chengdu University of TCM Affiliated hospital were collected in Pediatric outpatient from Mar.2012to Sep.2013, those of which met the criterion of accumulation of Henoch-Schonlein nephritis and were divided into two groups:TCM treatment group (36cases)and western medicine contrast group(36cases).36cases of TCM treatment group were treated by TCM comprehensive therapy, chose according to syndrome differentiation(Shaoyin lively card-Red styptic powder flavored、Shaoyin stasis resistance-The didan soup、Shaoyin fire certificate-New zhibaidihuang pill);36cases of Western medicine contrast group were given the routine therapy including prednisone piece,Dipyridamole tablets and Vitamin C tablets. The course of treatment is3months.Results:The clinical disease control rate of TCM treatment group is36.1%,the greater rate is75%,and the effective rate is94.4%;the cilinical disease control rate of western medicine contrast group is11.1%,the greater rate is38.9%,and the effective rate is80.6%. Comprising the two groups,there has a statistically significant difference between them (P<0.05). After the treatment comprising the variations of urinary protein, Urine occult blood,24-hour urinary protein quantity and urinary red blood cell count of two groups, there has a statistically significant difference between them(P<0.05),and in view of improving the clinical symptoms,reducing the plasma fibrinogen (FIB) and adverse reactions, TCM treatment group is better than Western medicine contrast group. Neither of the two groups have serious adverse reactions.Conclusion:TCM therapy treating children with Henoch-Schonlein nephritis has dramatic effects and great securities, and it’s worthy to promote application. But the long-term efficacy still needs to be further study.