Investigation On Infertility Status Of Married Women Of Childbearing Age In Haidian District

Objective To provide scientific basis for the prevention and treatment of infertility through investigating the prevalence of infertility among women who came for physical examination and of childbearing age in Haidian District, understanding the socioeconomic features, health conditions, and adverse exposure of infertile women and their spouses, understanding the medical utilization of infertile women in Haidian District, as well as comparing relevant factors of primary and secondary infertility.Methods The study group selection was conducted from April to September,2011through registration inquiry among women who came to take physical examination in10health service organizations in Haidian District. Targeted women were those aged20to49who had no contraception behavior between March1st,2010to February28th.2011. Date collected though questionnaires were general information, health conditions, adverse exposure conditions, menstrual conditions, past medical history, marital status, and spouse. EpiData3.1was used to conduct double entry of collected questionnaires, while SPSS17.0was used to take statistical analysis.Results1. Prevalence of infertility:registration inquiry was taken among11,727married women aged20to49from10health service organizations in Haidian District. There were1,016women who had no pregnancy among one year, among which912were infertile. The crude prevalence of infertility was7.8%and the age-standardized rate was7.0%. Of these912infertile women,148were primary infertility. The crude prevalence was1.3%and the age-standardized rate was1.5%.764were secondary infertility. The crude prevalence was6.5%and the age-standardized rate was5.5%.2. The socioeconomic features, health conditions, and adverse exposure of infertile women and their spouses. (1) Infertile womenThe average age was (38.15±6.80). Women aged above30covered58.1%and88.5%of primary and secondary infertility.76.6%were graduated from high school or above.89.9%were above5,000in terms of family income per head.50.4%were staff from government agencies, public institutions, or technical institutions.74.4%seldom did sports.32.1%were overweight while6.8%were underweight.5.3%had ever been exposed to radioactive or toxic substances. None of the women was smoker.24%drank more or less.82.5%had their menarche at11to15, while5.7%had their menarche after17.36%had irregular menstruation, of which the rate of abnormal menstrual cycle, abnormal menstrual quantity, and dysmenorrheal were20.2%,22.1%, and49.1%.61%had more than1time of sexual life per week. Among the infertile women,517had a history of gynecologic diseases, covering56.7%, among which, the morbidity of cervicitis was19.2%(175/912).15.7%women had a history of gynecological surgery.10.8%had ever taken hysteromyoma extirpation. Among women who were secondary infertility,50.7%had a history of abortion, among which, the rate of induced abortion was72.6%.(2) Spouse of infertile womenAge range:from21to73. The average age was (40.06±7.07).57.9%had a juniorl collage degree or above.52.1%were staff from government agencies, public institutions, or technical institutions.59.6%were overweight.25people,2.7%had ever been exposed to radioactive or toxic substances. There were425smokers, covering46.6%.53.9%had a history of drinking.2.5%had a history of reproductive system diseases.1.8%had ever taken the surgery of reproductive system. 3. Comparison of relevant factors of primary and secondary infertility.(1) Single-factor analysis:compared with primary infertility, women were more likely to be secondary infertile having following factors:age≥37, lower education level (below high school), abnormal weight, drinking, the menarche was before11or after15, having a history of gynecological operation, and having less than1time of sexual life per week. Correspondingly, spouses of these women were more likely to be:age>40, lower education level (below high school), abnormal weight, smoking, and drinking. The result is statistically significant ((P-value<0.05).Compared with secondary infertility, women were more likely to be primary infertile having following factors:higher education level (high school and above), working for government agencies or public institutions, and having Severe dysmenorrheal. Correspondingly, spouses of these women were more likely to be:working for government agencies or public institutions, exposure to radioactive or toxic substances, and having reproductive system diseases. The result is statistically significant ((P-value<0.05).(2) Multi-factor analysis:primary infertility may be related to history of dysmenorrheal (OR=3.57,95%CI=1.65-7.74, P=0.001). Other relevant factors may include:age≥37(OR=2.19,95%CI=1.09-4.41, P=0.028), spouses aged≥40(OR=1.86,95%CI=1.46-2.36, P=0.000), and spouses who smoke (OR=1.81,95%CI=1.07-3.06, P=0.027).4. Medical utilization of infertile women133women had child-bearing desire, coving14.6%, among which80(60.2%) went to see a doctor.Conclusion the prevalence of infertility among women from10health services organizations in Haidian District is similar to the national prevalence of infertility. Factors like irregular menstruation, history of gynecological disease, and abortion in women and factors like overweight, drinking, and smoking in their spouses have high incidence rates among infertile women and their spouses. These may be risk factors of infertility. Low child-bearing desire prevents infertile women from seeing the doctor. It is necessary to have further study and analysis on the influencing factors of infertility.