Study On The Correlation Between TCM Syndromes And Pathological Types In 113 Children With Henoch - Schonlein Purpura Nephritis And Its Related Factors

PurposeThrough the clinical observation of 113 cases of children with allergic purpura nephritis, fill in the allergic purpura nephritis questionnaire, comparing children with renal biopsy pathology results, analyze 113 cases of allergic purpura nephritis syndrome type of traditional Chinese medicine and the relationship between pathological type, and the epidemiological factors related to survey results were analyzed. MethodsSelect 113 cases in hospital between January 2011 and January 2011 in Shanxi Province traditional Chinese children with renal medicine outpatient and hospitalization, and diagnosis of allergic purpura nephritis, select cases all children with renal biopsy pathology report.Children with pathology, clinical diagnosis with clinical guidelines for a kidney volume a first edition "(people’s education press, 2011 [7], the kidney to learn a third edition(Ms. Wang, 2008) [8] as the reference standard.According to the disease nearly 10 years of relevant literature study, combined with the clinical characteristics of the disease, with reference to the law of the People’s Republic of China industry standard of traditional Chinese medicine, Chinese medical diagnosis of disease and treatment standard "(ZY/T001.4-94) " purpura syndrome classification and diagnosis based on " syndrome standards in [10].113 cases of children gather into standard, selected cases, truthfully fill in "allergic purpura nephritis questionnaire", record the onset time, the triggers, general situation, clinical symptoms and renal symptoms, blood routine, urine routine, liver function, renal function, etc., and according to the clinical manifestations of patients with the type test.Then the collected data for statistical processing, analysis and discussion on the distribution of each type of syndrome and the relationship between the pathological classification, and the epidemiology and the related influencing factors were investigated. The results of the studyAllergic purpura(Henoch- schonhin purpura, HSP) is the longest see children allergic necrotizing hemorrhagic small vasculitis, systemic clinical performance for pain or inflammation in joints, abdominal pain, skin thrombocytopenic purpura, hematuria and proteinuria [5]. Glomerular pathology change classification is given priority to with Ⅱlevel and level two, still give priority to with glomerular mesangial proliferation, consistent with Ⅲthe literature [6].According to the survey results of 113 cases, the main syndrome type and proportion of spleen and stomach syndrome(47.8%), wind burn winding type(11.5) and the air is not taken blood type(9.7%), Yin fire type(7.1%), blood heat type:(23.9%), consistent with most of the literature reports.Results in Ⅰlevel abnormal changes of glomerular mild(15.0%); Ⅱlevel pure mesangial proliferation, divided into focal/segmental, diffuse(39.8%); Ⅲmesangial proliferative, probably with less than 50% glomerular crescents formation or segmental lesions(such as hardening, adhesion, blood clots, necrosis, etc.)(35.4%); type with a level ⅣIII level pathological changes, but the lesion range is 50% ~ 75%(9.7%);Lesion types with level III grade V, but lesion range is > 75%(2.7%);Grade VI membrane proliferative glomerulonephritis(0.9%).Proportion of various pathologic type and most of these articles reported.8- this 14 years old children, often have disease more urgent, early is given priority to with the empirical, progress faster, this is consistent with the onset of the disease process.The author selected cases, in the majority with Ⅱ, Ⅲpathological types, the reports and documents, and the two level of TCM clinical manifestations of in spleen and stomach dampness heat, blood heat: two kinds of certificate is given priority to, and the higher the pathologic stage(Ⅳ, Ⅴ, Ⅵlevel), TCM clinical manifestation to deficiency syndrome(gas ejection, Yin deficiency of the fire) is given priority to, the prognosis is often poor.In addition, allergic purpura nephritis occurrence and development by season, age, period and other related factors.