Multimodal Magnetic Resonance Imaging Study Of Post Stroke Epilepsy

THE FIRST PART THE DIAGNOSIS OF POST-STRKE EPILEPSY BY DKIBackground: The incidence of stroke in China has always remained high.It should be noted that in recent years,the age of onset has tended to be younger,and subsequent post-stroke epilepsy has seriously affected the quality of life and prognosis of patients.Clinically,there is a lack of uniform norms and criteria for diagnosis and treatment of post-stroke epilepsy.Currently,the most valuable application for the diagnosis of primary epilepsy is neuroimaging research,in the past,many neuroimaging technologys have been applyed in primary epilepsy,the application of DKI in primary epilepsy is in its infancy.Neuroimaging studies on post-stroke epilepsy are reported less at home and abroad.This paper try to use diffusion kurtosis imaging(DKI)to explore post-stroke epilepsy,in order to obtain the imaging value of DKI for post-stroke epilepsy.OBJECTIVE: To investigate the effects of diffusion kurtosis imaging(DKI)on the damage of white matter microstructure in patients with post-stroke epilepsy.METHODS: Patients with PSE who met the inclusion criteria(case group,n=29)and matched epilepsy after infarction(control group,n=29)were selected.DKI data analysis method using DKE post-processing image to extract the region of interest,using IBM SPSS25.0 to compare and correlate the intra-and inter-group parameter values.Results: The case group:The MD value of the right putamen,right nucleus forelimb and hind limb was larger than the left side;the MK value of the right putamen and right nucleus forelimb was larger than the left side,and the MK value of the right thalamus was less than the Left side;there was no statistically significant difference between the FA values ? ? in various brain regions;The control group: the FA value of the right thalamus was smaller than the left side;the MD values of the right anterior limb,hind limb,right hippocampus,right thalamus,and right putamen were larger than left.Side;the MK value of the right putamen is greater than the left side.Conclusion: Diffusion kurtosis imaging(DKI)can detect microstructural and its lateral damage more sensitively through significant changes in parameter values.THE SECOND PART THE DIAGNOSIS OF POST-STRKE EPILEPSY BY RS-FMRIBackground: The incidence of stroke in China has always remained high.It should be noted that in recent years,the age of onset has tended to be younger,and subsequent post-stroke epilepsy has seriously affected the quality of life and prognosis of patients.Clinically,there is a lack of uniform norms and criteria for diagnosis and treatment of post-stroke epilepsy.Currently,the most valuable application for the diagnosis of primary epilepsy is neuroimaging research,and neuroimaging studies on post-stroke epilepsy are reported less at home and abroad.This paper uses resting brain functional imaging(rs-f MRI)to explore post-stroke epilepsy,in order to obtain the imaging value of resting brain functional imaging(rs-f MRI)for post-stroke epilepsy.OBJECTIVE: To investigate the effects of resting brain function imaging(rs-f MRI)on the changes of ALFF and Re Ho in patients with post-stroke epilepsy,to evaluate changes of different brain activity.METHODS: Patients with PSE who met the inclusion criteria(case group,n=39)and matched epilepsy after infarction(control group,n=39)were selected.rs-f MRI analysis was performed using resting-state brain function data(REST)and SPM methods.Results: The ALFF values of the bilateral frontal lobe,right hippocampus and bilateral nucleus forelimb were higher than those of the control group.The ALFF values of the bilateral occipital and parietal lobe were lower than those of the control group.The Re Ho values of the bilateral forehead,temporal lobe and biliateral nucleus forelimb were higher than those of the control group.The Re Ho values were lower than that of the control group in the bilateral occipital lobe and bilateral cerebellar hemisphere.Conclusion: Functional magnetic resonance imaging rs-fMRI can detect the changes of local brain tissue blood oxygen level-dependent signal synchronism caused by post-stroke epilepsy by using Re Ho and ALFF algorithm.