Extraction Of Syndrome Elements And Target Corresponding Combination Law Of Insomnia

ObjectiveThe so-called "not XianFang,only to find sleep",Chinese traditional medicine on insomnia(insomnia)highlights the remarkable effect and the characteristic of the clinical diagnosis and treatment,especially the thinking of treatment based on syndrome differentiation,such as Yin and Yang,the five internal organs,camp guard,qi-blood and so on but also the essence of diagnosis and treatment.But dialectical way of thinking has its limitation and irrationality,so Chinese medicine diagnostics,introduced the word "syndrome element",but the system research is still insufficient,reasonable and it is necessary to reform the specification."Extraction and stripping of this study is to through literature","Israel test certificate" and clinical science analysis inside" trial chuai,make insomnia syndrome elements extraction should be the combination again,as far as possible,faithfully reflect the wakefulness,clinical manifestations and syndrome factor correlation,syndrome factor and syndrome factor combination,such as structure,hope into wakefulness,the diagnosis and treatment for further reference.Methods 1)in ancient books,textbooks,periodicals,basis,experience and so on literature material as the basis,set by dimension reduction and the train of thought,etiology and pathogenesis of the literature into was,modern,qi and blood,Yin and Yang,the camp who invaded,phlegm and blood stasis,hot,stomach with nine pathogenesis classes;Split to insomnia complained of symptoms,mental state,fever,sweating,pain,facial features,food taste,language,voice,production waste,tongue veins 10 symptoms;Prescription drugs into nourish,clear heat,diarrhea,wet,water,temperature,and qi,xiaoshi,blood,phlegm,nerves,liver,benefit,astringent,wind dampness,begin to understand medicine 16 classes,card type into qi deficiency,Yang deficiency,blood deficiency,Yin deficiency,blood stasis,and qi stagnation,phlegm syndrome,wet,hot,cold,these table 11 syndrome elements;A comb for heart,liver,spleen,stomach,bravery,kidney 6,for clinical research of below order combination thought research foundation.2)to develop,the table of the insomnia clinical syndrome differentiation to collect general information of 271 cases of patients with insomnia,sleep chief complaint and accompanying symptoms,tongue and pulse condition,and in accordance with the "standard of diagnosis of disease and curative effect of traditional Chinese medicine," to the above description of 11 disease syndrome factors,through statistical software R,SPSS 19.0 and Apriori algorithm,respectively,using the association rules analysis,Euclidean distance arithmetic and system cluster analysis,the computing formula of objectively to single patients were classified into 11 syndrome elements,analysis of wakefulness,clinical characteristics,wakefulness,characteristics of sleep disorder,insomnia syndromes elements,sleep disorder and the correlation of syndrome,and insomnia syndromes elements combination rule.Results1)this research not mei,271 cases of male to female ratio is about 2:3,with 51 to 60 years old stage as the most common.Insomnia patients complained of the most common is difficult to fall asleep,sleep is not deep,much dream,and easy to wake up,wake up with more easily frightened paranoid symptoms,such as wake up is found in patients with force.God most often associated with fatigue,sleepiness,forgetfulness,limbs cold,dry mouth,pale tongue,teeth marks,yellow moss,pulse fine,shows mainly qi deficiency.At the same time,a high incidence of the following symptoms;headaches,migraine,vertex pain);Face green yellow,dark and light white;After eat,eat less difficult;Tastelessness not thirsty,thirsty and drink more,thirsty and don’t drink,or with mouth bitter;Constipation or loose stools.Night urination urine or yellow;Tongue thin white or red,fat big crack,indented tongue,tongue,thin uvula,sublingual collaterals blood stasis;Thin weak pulse,or floating number,or late.2)abnormal relationship between wakefulness and sleep cycle:unable to sleep and rem and non-rem sleep phases abnormalities related,not deep sleep and non-rem sleep phases Ⅲ,Ⅳ anomalies;More for the continuous state of rem dreams;Wake up,wake up early and wake up again to sleep and non-rem sleep Ⅰ period is related.Sleepless for the incubation period of sleep all night,easy to wake up when it happens,the phenomenon appear to sleep after waking up all night.3)according to the Euclidean distance calculation,the insomnia syndromes elements extraction syndromes comprehensive ranking 1 actions,second for qi deficiency syndrome,third to Yin deficiency syndrome,blood stasis in 4 patients,5 for blood deficiency syndrome,sixth for hot card,7th for water wet,the eighth of phlegm syndrome,for ninth exogenous,10th and qi stagnation syndrome,the 11th for the cold syndrome.4)the syndrome elements combination rule is:qi deficiency and Yin deficiency,Yang deficiency,blood deficiency,phlegm,blood stasis and heat combination;Yang deficiency and blood deficiency,Yin deficiency,and qi stagnation,phlegm,blood stasis,dampness,such combination;Yin deficiency and blood deficiency,phlegm,blood stasis,dampness,heat,such combination;Blood deficiency and phlegm,blood stasis,dampness,heat,and qi stagnation,by combining business health disorders;Blood stasis and dampness,phlegm,heat combination;Phlegm,dampness,heat two combination.5)a sleep disorder and the correlation of syndrome is:qi deficiency syndrome and the group of related sleepless,after waking up all night;Yang deficiency is associated with difficulty falling asleep,sleep is not deep;Yin deficiency syndrome in sleep is not deep,sleepless;Blood deficiency syndrome in difficult to fall asleep,wake up to sleep,awake;And qi stagnation syndrome,blood stasis,in cold and wet in easy to wake up,wake up;Heat syndrome,phlegm syndrome,a monograph on the basis of the early up,easy to wake,there are more than a dream.Conclusion1)clinical should distinguish "pathogenesis,syndrome,syndrome elements",the relationships between the three pathogenesis is contact theory explanation of the objective factors,expression of disease processes and nature;Type the name used to express a set of symptoms,symptoms of each only measures the overall state of the variable;Is the smallest unit of syndrome and syndrome elements,including disease and illness,to summarize and reflect the nature of the disease.2)USES the syndrome elements dimension reduction order thinking,should be the combination of methods,to improve the accuracy and flexibility,can be in clinical understanding of hpi,etiology and pathogenesis,etc,according to the symptoms,signs,tongue,the pulse to determine,then define a variegated liters order card,to use drug formula for clinical use of dimension reduction liters order is Jane yu numerous important dialectical thinking.3)apply association rule,Euclidean distance,three kinds of operation system cluster analysis,can reduce the subjectivity of syndrome differentiation,improve the clinical objective basis.Total 4)wakefulness and pathogenesis for the virtual reality,Yin and Yang,with qi and blood deficiency,deficiency of Yin and Yang,qi and blood stasis,phlegm dampness,heat,cold,exogenous empirical as standard.5)prediction is derived,wakefulness,seven complained of syndrome elements is derived,the complaints of the syndrome elements can predict opposite not mei,in clinical diagnostic reference complement each other.6)dimension reduction order syndromes elements of thinking,is helpful to diagnosis and treatment was made in both for again on this,don’t ignore the symptomatic treatment and symptoms at the same time.According to the characters of standard of wakefulness,this virtual to real,symptomatic treatment,combining syndrome performance severely,give full play to the traditional medicine of traditional Chinese medicine in essence not mei(insomnia)on the diagnosis and treatment.