| Objective: To investigate the related factors of the formation of cerebral aneurysms, the related factors of ruptured intracranial aneurysms(CA), the relationship between cerebral vascular morphology and cerebral aneurysms and provide a reference for the diagnosis and treatment of aneurysms.Methods:(1) the data of 190 patients with CA in our hospital from December 2014 to July 2012 were collected, and the gender, age, smoking history, drinking history, hypertension, coronary heart disease history were recorded. Measurement of the angle of the A2 segment of the anterior cerebral artery. The relationship of CA occurrence and clinical characteristics of patients with A2 segment of anterior cerebral artery, and the correlation factors of the two factors were analyzed.(2) the clinical data of 120 patients with CA in our hospital from Dec,2014 to May,2013 were collected. The patients’ gender and age were recorded. The original data were acquired by CTA scanning. The calculated ratio of length and width of aneurysm neck artery aneurysm, arterial tumor capsule presence. The relationship between CA rupture and sex, age, location of CA, length of tumor, maximum diameter, width of tumor and the width of the tumor was analyzed.(3) 190 patients with subarachnoid hemorrhage were collected from October 2014 to July 2013 in our hospital. The DSA examination and MRA examination and CA examination were performed to analyze the relationship between the CA and A2.Results:(1) there were no significant differences between male and female according to the age of <30,30~40, 40~50, 50~60, 60~70, >70 six group. The incidence rate of CA in male and female was higher in the age of40~50, 50~60, 60~70, especially in the age of 50~60. The incidence of hypertension in CA group was significantly higher than that in the control group(P<0.05), the 0.05 groups had no statistical significance(P > two). Logistic multiple regression analysis showed that gender, age and hypertension were independent risk factors for CA formation.(2) the rupture rate of the anterior communicating artery aneurysm was significantly higher than that of other sites, followed by the posterior communicating artery aneurysm, and the lowest rupture rate was the basilar artery aneurysm(P<0.05). The age of the patients was significantly higher than that of the non ruptured group, and the difference was statistically significant(P<0.05). The percentage of women in the rupture group was significantly higher than that in the non ruptured group, the difference was statistically significant(P<0.05), the maximum diameter of the aneurysm was(8.9±2.4) mm, the maximum diameter of the aneurysm was(7.2±2.0) mm, the maximum diameter of the rupture group was significantly increased, the difference was statistically significant(P < 0.05). With the maximum diameter of the aneurysm is 10 mm for the sector grouping, aneurysm < 10 mm into the < 10 mm group, the aneurysm is equal to or more than 10 mm into is equal to or more than 10 mm group. Results show that, 150 aneurysm, aneurysm of the maximum diameter of < 10 mm has 117 case, 78.0%, the rupture rate was 51.3%. Aneurysm diameter greater than 10 mm 33, accounted for 22%, rupture rate was 78.8%(26/33). Is equal to or more than 10 mm group rupture rate was significantly higher than that of < 10 mm group, the difference is statistically significant(P < 0.05), rupture of aneurysm group average tumor body length and AR respectively(6.8± 2.2) mm,(2.2 ± 0.9). The average length of the tumor, the average width of the tumor, and the width of the tumor were mm(4.7±2.2) AR,(1.4 ±0.4), respectively. The average tumor volume of aneurysm in the rupture group was significantly higher than that in the non ruptured group, and the difference was statistically significant(P < 0.05). 150 aneurysms, a total of 81 existing Ascomycetes, accounting for 54%. Group a total of 79 aneurysm rupture, of which 43 ascus unruptured group 71 aneurysms, of which 37 by the ascomycete, rupture group ascus was significantly higher than that of the unruptured group, the difference is statistically significant(P < 0.05).(3) the appearance of anterior communicating artery aneurysm male was significantly higher than that in female, communicating artery aneurysm male incidences of the later was obviously lower than that in the female, the difference is statistical significance(P < 0.05), multiple aneurysms, M1 bifurcation aneurysms, other parts of the aneurysm in the distribution of male and female no unification difference(P > 0.05). In all ages, there was no significant difference between males and females in CA incidence. The incidence rate of CA in male and female was higher in the age of 50 to 40, 50 to 60 and 60 to 70, especially in the age of 50 to 60(CA). There were 92.3% dominant types in the front of the traffic arteries, and there was significant difference between the dominant side of the normal persons(P<0.05), which indicated that the anterior communicating artery aneurysm was associated with the dominant blood flow in one side. There were 33 cases of anterior circulation and 35 cases with standard equilibrium, and the difference was statistically significant(P < 0.05). Anterior communicating artery aneurysm, after communicating artery aneurysm, multiple aneurysms in patients with cerebral vascular morphology variation rate than that of the normal human brain vascular morphology was significantly increased, but M1 distal bifurcation aneurysm cerebral vascular morphology no statistical difference(P > 0.05). The mean angle between the anterior segment of the A2 segment of the anterior cerebral artery was 175.3, and the mean value of the patients with no tumor was statistically significant(P<0.05).Conclusion:(1) The formation of CA is related to age, sex, hypertension and cerebral blood vessel. Therefore, it is necessary to consider these risk factors to improve the prognosis of patients.(2) The CA occurred site, the patient’s age and sex, the tumor body length, AR values, the tumor exist ascus are closely related with rupture, which is an important risk factor, so early assessing the risk of CA patients has guiding significance to the clinical treatment of CA.(3) the change of cerebral vascular morphology is an important factor in the formation of CA, but its formation is influenced by many factors, the specific mechanism needs further study. |
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