Single-nostril Transsphenoidal Approach For Pituitary Adenomas: Endoscopic Surgery Vs Microsurgery

Objective:To compare efficacy and safety of single-nostril transsphenoidal surgery for pituitary adenomas between endoscopic surgery and microsurgery. Methods:Data of patients who were treated in the first affiliated hospital of XinJiang Medical University from January2002to June2012were analyzed. Results:There are690patients with pituitary adenomas.The average age was47.1(range7to79)years old, There are no difference between two groups about rate of total resection,visual function recovery rate,endocrine reief rate, average operative time(time from the use of epinephrine to shrink the nasal mucosa of nasal packing foam expansion), the average bleeding volume.But the average time of stay in hospital in microsurgery group was higher than that in endoscopic group. The patients after endoscopic surgery feel more comfortable. Conclusion:Transsphenoidal surgery of pituitary adenoma can not only make use of endoscopic bu also under the microscope; Two surgical techniques inpostoperative hospitalization time were significantly different, Endoscopic surgery is superior to operation under the microscope. In bleeding volume, the effective rate of resection, postoperative complications, symptoms; and other aspects of tumorrecurrence in both groups no significant differences; the effective rate of resection of the two operative group Implied endoscopic surgery issuperior to prompt surgical microscope.