Clinical And Experiment Studies Of The Zhuang Medicine Kuijie Plug On Treating UC

Goal:1. To observe the clinical effect of the Zhuang Medicine kuijie pill on UC.2. To Observe the effects of the Zhuang Medicine kuijie pill on model animal’s plasma PAF, E. coli colonies amount in intestines content, and pathology changes of the colon organization, etc.3. Through this topic research, to reveal the mechanism of the Zhuang Medicine kuijie pill on treating UC, and to develops one kind of the new medicine of treating UC.Method:1.60 patients were randomly divided into the treatment group and the comparison group, each group with 30 examples. Separately gives the Zhuang Medicine kuijie pill and SASP plug medicine through giving medicine after anus to observe the various targets change of treatment around。2. After marking numbers and lotting, the model animal were randomly divided into the Zhuang Medicine kuijiepill group, the SASP plug group and model animal group, each group of 8. Takeing 8 health Wistar big rats in addition for the health comparison group.separately gives Zhuang Medicine kuijie pill, SASP plug medicine, and the matrix plug of not containing medicine, to observe the various targets change of treatment around。Results:1. In the comparison of clinical effect, Chinese medicine symptom curative effect, Chinese medicine symptoms integral of treatment Around, symptoms clinical effect, intestines mucous membrane curative effect through mirror examines, and intestines mucous membrane pathology curative effect, and so on, the treatment group obviously surpasses the comparison group (P<0.05)。2. In the comparison of model animals’weight, model animal plasma PAF, and the quantity of E.coli in intestines content, Zhuang Medicine kuijiepill group and with SASP plug group mutually quite even not obvious difference (P> 0.05). In the comparison of visual observation damage, the damage integral, the ulcer number, and the ulcer area, Zhuang Medicine kuijiepill group and with SASP plug group mutually quite has the obvious difference (P<0.05)Conclusion:1. The Zhuang Medicine kuijie pill has good and accurate clinical curative effect on UC.2. The Zhuang Medicine kuijie pill may improve the model animal pathology change on colon, reduces the amount of plasma PAF in blood, and the quantity of E.coli in intestines content. It is possibly the one of mechanisms for treating UC.