The Study On Burden Of Disease Attributing To Water In "Cancer Village" Of Huaihe River Basin

In the constant struggle with the disease, the people have noted that health and environmental factors on the important role of environmental factors on people first took note of the important impact of acute infectious diseases, gradually, the environment on the role of chronic non-communicable diseases are also caused attention.With the rapid development of China's economy in recent years, modern industry and agriculture bring the increasing pressure to the environment. The past 20 years, many polluting industrial enterprises is transferred from the urban to rural areas, to become a new source of pollution in rural areas, environmental pollution and lead to high incidence of cancer reported quite frequently. Cause of cancer is very complex and long-term exposure to environmental pollutants, is characterized by a low dose, and the nature of different pollutants, the cost of laboratory tests is very high, not a routine test. Therefore, the environmental factors, risk assessment methods and index system become a key component for the study on the development impact of environmental pollution on cancer.However, due to various reasons, lack of environmental pollution on the health hazards related data creates barriers to the study on environmental factors and cancer incidence and mortality great. In 2005, the Huaihe River basin in the media reported the existence of "cancer villages", and doubt directed at the polluted water of Huaihe River! The incident caused the same attention from the central to local goverment, which to research the relationship between environment and cancer brought a rare opportunity. This study was done under such historical conditions.Researchers have chosen Shenqiu of Henan Province, Yongqiao district of Anhui Province and Xuyi County of Jiangsu Province as a research site, in which the media reported "cancer villages" and its surrounding villages as the study area, but the village which are away from the river, high altitude as a control area. The research includes the death and prevalence investigations. Death investigations compared the use of the current international advanced tools-verbal autopsy (VA). In these work, also conducted a survey of risk factors associated with malignancy, in order to find the etiology of a wide range.Because of the lack of environmental data and health data based on both work, so study the relationship between the two elements into a number of original:we use chemical oxygen demand (CODCr) as an indicators of water pollution of the environment; use of spatial interpolation was missing pollution data area information; use of long-term trend estimate the total cumulative exposure; use a variety of factors to adjust the water environment, the direct role of the tumor.The study of diseases, including stomach, esophageal and liver cancer three gastrointestinal cancer, and health indicators, we use the disability adjust life year (DALY), their relationship is in accordance with the WHO recommendation of The comparative risk assessment (CRA) framework due to:first, to estimate the various levels of pollution exposure, and then calculated according to the prevalence of RR values of death, and finally estimate the PAF and attributable burden of disease.After analysis, we found that the Shenqiu considered as the three leading cancer DALYs for the 2983 total,19.7 per thousand people, of which 1834 men, with an average 23.8 per thousand and females 1149,15.4 per thousand; Anhui Yongqiao total area considered as the three leading cancer DALYs as the 2532 average of 17.0 per thousand, of which 1882 men,24.8 per thousand women of 650, with an average 8.8 per thousand; calculated by Jiangsu Xuyi three kinds of cancer, leading to a total DALYs for the 1419 average of 9.2 per thousand, of which 887 men, with an average of 11.5 per thousand women of 532, with an average of 6.9 per thousand.As can be seen from the above results, the burden of disease of Shenqiu and Yongqiao is heavier than it of Xuyi, especially men, the burden per thousand reached the Xuyi 2 times. At same time, it is also higher than the national average. The PAF of Shenqiu is 0.8351 in men, and women's is 0.8131. Further, the DALYs attribute to water, male's is 1532, females'is 934, and PAF of Yongqiao is 0.8511 for males, and for females, PAF is 0.8215. Further calculations due to disease burden, DALYs for male is 1602 and 534 for females. (Due to lack of environmental data, Xuyi has no attribution of disease burden.)Further evidence of the pollution of water environment will adversely human health effects that may lead to the occurrence of gastrointestinal cancer from our research; at the same time, the reality of our situation is also explored an alternative frame for assessing the risk of for health, especially chronic disease. Simultaneously, our study provides the useful clues to similar study, too.