| Professor Daiyuguang was one of famous TCM doctors in PLA.He dabbled in internal medicine,gynecology and pediatrics,especially accumulated abundant clinical experience in miscellaneous disease.He thought students should read all kinds of books and well-known medical works carefully to apply them well and should be diligent,bookish,constant,thinking and realizing.He emphasized that human,heaven and earth should be a trinity and the constitution and the influences of environmental factors should be considered in diagnosis and treatment Activity and calmness should be integrated and cold and warm chinese medicine should be used simultaneously.He formed his special idea of finding the way to expel the evil and reduction must be used when tonification was used. Also he put forward that regulating the functional activities of Qi was the first step to treat spleen and stomach diseases,protecting the Yang qi of the spleen and kidney and benefiting Yin essence of the liver and kidney was the root.Professor Dai's common used and proved formulas embodied his academic thoughts and selection of modifying prescription from pharmacology of TCM formula.Congestive Heart Failure(CHF) was a compound clinical syndrome and the severest stage of all kinds of heart disease,characterized by high morbidity,being difficult to be treated and being main cause of death of cardiovascular disease.In recent years,principles of treatment in western medicine changed from cardiac stimulating,diuresis and vascular relaxation to blocking myocardial remodeling factor and stopping and reversing myocardial remodeling,greatly decreasing mutilation rate and case fatality rate of CHF.Nevertheless,to some extent,the use of those drags was limited clinically because natural pathogenic process of CHF couldn't be completely blocked by those drugs and side effects of those drugs. Professor Daiyuguang thought CHF's pathogenesis was a vicious circle of deficiency syndrome mingles with excess caused by deficiency of yang, stagnation of blood stasis and fluid-retention stagnation in the interior after he studied a lot of TCM classics like Yellow Emperor's Canon Internal Medicine. Warming Yang and benefiting Qi and removing blood stasis and promoting diuresis were the main therapeutic methods.In different stage,different method of treatment should be used.In the initial stage,warming Yang and benefiting Qi should be the main method of treatment.In the latest stage,Warming Yang and benefiting Qi and removing blood stasis and promoting diuresis should be used simultaneously.In the stable stage,warming Yang and benefiting Qi should be the main method of treatment.In the outbreak stage,removing blood stasis and promoting diuresis should be the main method of treatment.Qiangxin decoction was a proved formula which was used by professor Daiyuguang to treat CHF and had therapeutic effect of supplementing qi and warming yang,removing blood stasis and promoting diuresis.Clinical research has been done to prove therapeutic effect of the formula.This study was a random positive medicine controlled trial.Therapeutic effect and adverse event of Qiangxin decoction was observed simultaneously.It indicated that Qiangxin decoction was superior to Qili qiangxin capsule in total effectiveness rate,TCM syndrome effectiveness rate,and et al,8 weeks after treatment.Ⅱ,Ⅲgrade heart function,symptoms like palpitation,chest distress,short breath and et al,signs like heart rate(HR≥100分),edema of lower limbs and et al,and EF,SV,6ms walking test improved in both groups and the trial group was superior to the control group(P＜0.05或P＜0.01).And there was no significant difference in improvingⅣgrade heart function,aversion to cold and cold limbs and signs like heart rate(HR＜60次/分) between the two groups(P＞0.05) after the treatment.No obvious adverse event was found in the two groups. |
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