| Osteoporosis (OP) is a common disease and frequently occurring among population, especially does harm to aged people's health. Along with the advance of life expectancy populate of people and aging sociality, the prevention and therapy of osteoporosis has attracted more attention of medical affairs perennials .With the development of social and the transitions of the health view and medical-model , the assessment of quality of life (QOL) in clinical trials has accepted by more and more medical affairs perennials. In our country , the study of QOL is starting. Compared with modern medicine science , traditional Chinese medicine (TCM)pay close attention to the view of person of their health among physical and mental health .TCM see the body as a whole , this opinion is as same as the idea of QOL .Bring the assessment of quality of life into the distinguishability and evaluation of traditional Chinese medicine ,we can make these more objective and scientific .It make important significance for the development of TCM.Based on the reviewing and summarizing the documents of the concerned theory , in the theoretical research, we explored the etiological , pathogenesis and regularity of diagnosis and treatment .The theory of traditional Chinese medicine revealed"kidney governs the bone","spleen is the root of later heaven"and"when there is stoppage ,there is pain". The study indicated that the basical pathogenesis of POP was spleen-kidney vacuity detriment ,bowl-gastrointestinal depression and stagnation, and disharmony of qi and blood. By using theory of traditional Chinese medicine"tongbu bingyong", the principles of therapy should be a comprehensive utilization of supplement the spleen and kidney , freeing the bowels and downbear turbidity , harmonie the qi and blood .Clinical study 1 :The study explored the relationship between the syndrome types differentiated by traditional Chinese medicine and the quality of life (QOL) in patients with osteoporosis (OP). The QOL in patients was investigated with Short Form-36 questionnaire (SF-36) , and compared with that of the non-OP people; the TCM syndrome type was differentiated at the same time by the outcomes of symptoms acquired from the questionnaire. The score of all the domains of QOL was respectively lower in the OP patients than that in the non-OP subjects. The score of some domains of QOL showed correlation with different TCM syndrome types. QOL of OP patients significantly decreased. The variation of syndrome types could significantly influence some domains of QOL.Clinical study 2 : The study observed the influence of traditional Chinese medicine to the quality of life in the primary osteoporosis (POP) patients . The study wanted to explore the therapeutics effects of traditional Chinese medicine (TCM) and pharmacy on primary osteoporosis (POP) to provide the reference for preventing chronic disease and improving the elder's quality of life. The QOL in patients was investigated with Short Form-36 questionnaire (SF-36) , 80 patients with POP in community were bone-scanned in lumbar vertebrae and thoghbone to measure the bone mineral density(BMD). They had finished the SF-36 QOL survey questionnaire and TCM syndrome investigation . We randomly selected 40 of them for TCM treated group. The patients were observed for one treatment courses with QOL estimated by Short Form-36 questionnaire ,and referred to the traditional evaluating indexes of clinical efficiency. After three months of treatment,there was significantly difference between the two groups. QOL in the TCM treated group was improved after treatment with the improvement of scores in all domains , while it in domains of role -physical,bodily pain,general health,social functioning,vitality,role emotional and mental health ,there was statistical significance. ( P< 0.05). The score of QOL in six of the eight domains (physical functioning,role-physical,bodily pain,social functioning,vitality and mental health) were higher in the TCM treated group than those in the control group ( P < 0.05) , and no significant difference was shown between the domains of general health and role emotional of the two groups ( P > 0.05).All things we had done suggested that the"tongbu bingyong formula"can improve the bone mineral density and increase the quality of life in the primary osteoporosis (POP) patients. It might be one of the mechanisms for this therapy .It showed that more research into the therapy of TCM and quality of life are needed.The innovation of this study : The study explored the connotation of life quality and its interrelation with TCM , application of life quality at department of dermatology . The study indicated that the quality of life can objectively reflect the TCM characteristic and put forward the quality of life will be includedin the assessment system of TCM therapeutic effect of OP disease.The study explored the relationship between the syndrome types differentiated by traditional Chinese medicine and the quality of life (QOL) in patients with osteoporosis (OP). The quality of life (QOL) in patients with osteoporosis (OP) was lower than non-OP people . The score of some domains of QOL showed correlation with different TCM syndrome types.The study observed the influence of traditional Chinese medicine to the quality of life in the primary osteoporosis (POP) patients . The study explored the therapeutics effects of traditional Chinese medicine (TCM) the"tongbu bingyong formula"can improve the bone mineral density and increase the quality of life in the primary osteoporosis (POP) patients. They both have very importance sense in the investigation and evaluation of clinic in osteoporosis patient by the traditional Chinese medicine.
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