Rectal Appropriate Conformal Radiation Therapy Of Clinical And Experimental Studies

1. Prognostic factor and pattern of failure of rectal cancer—an analysis of 327 patientsObjective: To study how the TNM stage, pathologic classification and adjuvant treatment influence the prognosis of rectal cancer, and give an evidence of evaluating prognosis accurately and selecting reasonable treatment methods for rectal cancer. Methods From January 1994 to October 1997, 327 patients with rectal cancer ( on 1997 UICC stage system: stage I 48, stage II 121, stage III 150 and stage IV 8 ) were treated by surgery included Miles 171, Dixon 136, Hartmman 15 and other ways of surgery 5. Among of all patients, male 177, female 150, 320 underwent radical resection and 7 palliation. 247 cases received postoperative radiotherapy with a median dose of 50 Gy. Follow up time ranged from 5 to 105 months with a median of 65. Results: The overall survival at 1, 3 and 5 years for all patients were 93.6%, 73.1% and 61.5%, respectively. The overall 5-year survival rates were 87.5%, 75.2%, 45.3% and 0 for stage I , stage II ,stage III and stage IV, respectively. Stage III were divided into two groups according to N state (N1 and N2), the overall 5- year survival rates were 58.0% and 28.6% for...