Clinical And Mechanism Of Action Of Acupuncture Treatment Of Non-insulin-dependent Diabetes Research

The paper was composed of three parts as follows:Theoretical study previewed the treatments of non-insulin-dependent diabetes mellitus (NII)DM) with acupuncture-moxibustion and the mechanism of acupuncture-moxibustion treating NIDDM. Clinical study observed 45 fat patients of NIDDM treated with acupuncture-moxibustion, the results showed that the acupuncturemoxibustion could obviously decrease concentrations of FINS, FC-P, TC,TG,LDL-C, while increase that of HDL-C, improve insulin resistance. 28 of 45 were cured,1 lof 45 were improved, 6 of 45 had not any change after treatment, the total effective rate was 86.6%. Study of mechanism observed how acupuncture get effecfs on rats of NIDDM.The results showed that acupuncture could decrease concents of FiNS and FC-P, increase the tolerance of NIDDM rats towards oral glucose,change the structures of insulin ~ cells and liver cells, improve the secretive function of insulin P cells,increase the discharge frequence of ARC cells,regulate the concents of NA,5-HIAA,5-HT, DA, enhance adipocytes abilities of transporting glucose.The relative analyse showed that the regulation of acupuncture to ARC was the key factor for the changes of PBG, FiNS, FC-P and glucose transportation. It indicates that the regulation of acupuncture to ARC is one of the most important links to the treatment for NI1)DM.